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GW779439X and Its Pyrazolopyridazine Derivatives Inhibit the Serine/Threonine Kinase Stk1 and Act As Antibiotic Adjuvants against β-Lactam-Resistant Staphylococcus aureus.
Schaenzer AJ, Wlodarchak N, Drewry DH, Zuercher WJ, Rose WE, Ferrer CA, Sauer JD, Striker R. Schaenzer AJ, et al. Among authors: sauer jd. ACS Infect Dis. 2018 Oct 12;4(10):1508-1518. doi: 10.1021/acsinfecdis.8b00136. Epub 2018 Aug 15. ACS Infect Dis. 2018. PMID: 30059625 Free PMC article.
Penicillin Binding Protein 1 Is Important in the Compensatory Response of Staphylococcus aureus to Daptomycin-Induced Membrane Damage and Is a Potential Target for β-Lactam-Daptomycin Synergy.
Berti AD, Theisen E, Sauer JD, Nonejuie P, Olson J, Pogliano J, Sakoulas G, Nizet V, Proctor RA, Rose WE. Berti AD, et al. Among authors: sauer jd. Antimicrob Agents Chemother. 2015 Nov 2;60(1):451-8. doi: 10.1128/AAC.02071-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26525797 Free PMC article.
In Silico Screen and Structural Analysis Identifies Bacterial Kinase Inhibitors which Act with β-Lactams To Inhibit Mycobacterial Growth.
Wlodarchak N, Teachout N, Beczkiewicz J, Procknow R, Schaenzer AJ, Satyshur K, Pavelka M, Zuercher W, Drewry D, Sauer JD, Striker R. Wlodarchak N, et al. Among authors: sauer jd. Mol Pharm. 2018 Nov 5;15(11):5410-5426. doi: 10.1021/acs.molpharmaceut.8b00905. Epub 2018 Oct 18. Mol Pharm. 2018. PMID: 30285456 Free PMC article.
113 results