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Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design.
Thépaut M, Guzzi C, Sutkeviciute I, Sattin S, Ribeiro-Viana R, Varga N, Chabrol E, Rojo J, Bernardi A, Angulo J, Nieto PM, Fieschi F. Thépaut M, et al. Among authors: sattin s. J Am Chem Soc. 2013 Feb 20;135(7):2518-29. doi: 10.1021/ja3053305. Epub 2013 Feb 8. J Am Chem Soc. 2013. PMID: 23360500
Unique DC-SIGN clustering activity of a small glycomimetic: A lesson for ligand design.
Sutkeviciute I, Thépaut M, Sattin S, Berzi A, McGeagh J, Grudinin S, Weiser J, Le Roy A, Reina JJ, Rojo J, Clerici M, Bernardi A, Ebel C, Fieschi F. Sutkeviciute I, et al. Among authors: sattin s. ACS Chem Biol. 2014 Jun 20;9(6):1377-85. doi: 10.1021/cb500054h. Epub 2014 May 6. ACS Chem Biol. 2014. PMID: 24749535
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist.
Thépaut M, Luczkowiak J, Vivès C, Labiod N, Bally I, Lasala F, Grimoire Y, Fenel D, Sattin S, Thielens N, Schoehn G, Bernardi A, Delgado R, Fieschi F. Thépaut M, et al. Among authors: sattin s. PLoS Pathog. 2021 May 20;17(5):e1009576. doi: 10.1371/journal.ppat.1009576. eCollection 2021 May. PLoS Pathog. 2021. PMID: 34015061 Free PMC article.
Carbohydrates: A phenol sandwich fights diabetes.
Bernardi A, Sattin S. Bernardi A, et al. Among authors: sattin s. Nat Chem Biol. 2015 Sep;11(9):635-6. doi: 10.1038/nchembio.1888. Nat Chem Biol. 2015. PMID: 26284669 No abstract available.
Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.
D'Annessa I, Sattin S, Tao J, Pennati M, Sànchez-Martìn C, Moroni E, Rasola A, Zaffaroni N, Agard DA, Bernardi A, Colombo G. D'Annessa I, et al. Among authors: sattin s. Chemistry. 2017 Apr 19;23(22):5188-5192. doi: 10.1002/chem.201700169. Epub 2017 Mar 22. Chemistry. 2017. PMID: 28207175 Free PMC article.
39 results