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Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1.
Mabe NW, Huang M, Dalton GN, Alexe G, Schaefer DA, Geraghty AC, Robichaud AL, Conway AS, Khalid D, Mader MM, Belk JA, Ross KN, Sheffer M, Linde MH, Ly N, Yao W, Rotiroti MC, Smith BAH, Wernig M, Bertozzi CR, Monje M, Mitsiades CS, Majeti R, Satpathy AT, Stegmaier K, Majzner RG. Mabe NW, et al. Among authors: satpathy at. Nat Cancer. 2022 Aug;3(8):976-993. doi: 10.1038/s43018-022-00405-x. Epub 2022 Jul 11. Nat Cancer. 2022. PMID: 35817829 Free PMC article.
c-Jun overexpression in CAR T cells induces exhaustion resistance.
Lynn RC, Weber EW, Sotillo E, Gennert D, Xu P, Good Z, Anbunathan H, Lattin J, Jones R, Tieu V, Nagaraja S, Granja J, de Bourcy CFA, Majzner R, Satpathy AT, Quake SR, Monje M, Chang HY, Mackall CL. Lynn RC, et al. Among authors: satpathy at. Nature. 2019 Dec;576(7786):293-300. doi: 10.1038/s41586-019-1805-z. Epub 2019 Dec 4. Nature. 2019. PMID: 31802004 Free PMC article.
Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection.
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Schmitz CO, Mumbach MR, Limaye A, Wei J, Alfajaro MM, Parker KR, Chang HY, Horvath TL, Carette JE, Bertozzi C, Wilen CB, Satpathy AT. Flynn RA, et al. Among authors: satpathy at. bioRxiv [Preprint]. 2020 Oct 6:2020.10.06.327445. doi: 10.1101/2020.10.06.327445. bioRxiv. 2020. PMID: 33052334 Free PMC article. Updated. Preprint.
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette JE, Bertozzi CR, Wilen CB, Satpathy AT. Flynn RA, et al. Among authors: satpathy at. Cell. 2021 Apr 29;184(9):2394-2411.e16. doi: 10.1016/j.cell.2021.03.012. Epub 2021 Mar 11. Cell. 2021. PMID: 33743211 Free PMC article.
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.
Weber EW, Parker KR, Sotillo E, Lynn RC, Anbunathan H, Lattin J, Good Z, Belk JA, Daniel B, Klysz D, Malipatlolla M, Xu P, Bashti M, Heitzeneder S, Labanieh L, Vandris P, Majzner RG, Qi Y, Sandor K, Chen LC, Prabhu S, Gentles AJ, Wandless TJ, Satpathy AT, Chang HY, Mackall CL. Weber EW, et al. Among authors: satpathy at. Science. 2021 Apr 2;372(6537):eaba1786. doi: 10.1126/science.aba1786. Science. 2021. PMID: 33795428 Free PMC article.
Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis.
Huang X, Ferris ST, Kim S, Choudhary MNK, Belk JA, Fan C, Qi Y, Sudan R, Xia Y, Desai P, Chen J, Ly N, Shi Q, Bagadia P, Liu T, Guilliams M, Egawa T, Colonna M, Diamond MS, Murphy TL, Satpathy AT, Wang T, Murphy KM. Huang X, et al. Among authors: satpathy at. Immunity. 2021 Jul 13;54(7):1417-1432.e7. doi: 10.1016/j.immuni.2021.04.015. Epub 2021 May 17. Immunity. 2021. PMID: 34004142 Free PMC article.
A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance.
Warshauer JT, Belk JA, Chan AY, Wang J, Gupta AR, Shi Q, Skartsis N, Peng Y, Phipps JD, Acenas D, Smith JA, Tamaki SJ, Tang Q, Gardner JM, Satpathy AT, Anderson MS. Warshauer JT, et al. Among authors: satpathy at. J Exp Med. 2021 Aug 2;218(8):e20210759. doi: 10.1084/jem.20210759. Epub 2021 Jun 11. J Exp Med. 2021. PMID: 34115115 Free PMC article.
Repertoire Remodeling through CD4+ T-cell Depletion.
Yao W, Satpathy AT. Yao W, et al. Among authors: satpathy at. Cancer Immunol Res. 2021 Jun;9(6):601. doi: 10.1158/2326-6066.CIR-21-0301. Cancer Immunol Res. 2021. PMID: 34365414
NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity.
Richards RM, Zhao F, Freitas KA, Parker KR, Xu P, Fan A, Sotillo E, Daugaard M, Oo HZ, Liu J, Hong WJ, Sorensen PH, Chang HY, Satpathy AT, Majzner RG, Majeti R, Mackall CL. Richards RM, et al. Among authors: satpathy at. Blood Cancer Discov. 2021 Sep 16;2(6):648-665. doi: 10.1158/2643-3230.BCD-20-0208. eCollection 2021 Nov. Blood Cancer Discov. 2021. PMID: 34778803 Free PMC article.
ecDNA hubs drive cooperative intermolecular oncogene expression.
Hung KL, Yost KE, Xie L, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, Chamorro González R, Weiser NE, Chen C, Valieva ME, Wong IT, Wu S, Dehkordi SR, Duffy CV, Kraft K, Tang J, Belk JA, Rose JC, Corces MR, Granja JM, Li R, Rajkumar U, Friedlein J, Bagchi A, Satpathy AT, Tjian R, Mundlos S, Bafna V, Henssen AG, Mischel PS, Liu Z, Chang HY. Hung KL, et al. Among authors: satpathy at. Nature. 2021 Dec;600(7890):731-736. doi: 10.1038/s41586-021-04116-8. Epub 2021 Nov 24. Nature. 2021. PMID: 34819668 Free PMC article.
256 results