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The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.
Takatsuno Y, Mimori K, Yamamoto K, Sato T, Niida A, Inoue H, Imoto S, Kawano S, Yamaguchi R, Toh H, Iinuma H, Ishimaru S, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Miyano S, Sugihara K, Mori M. Takatsuno Y, et al. Among authors: sato t. Ann Surg Oncol. 2013 Apr;20(4):1395-402. doi: 10.1245/s10434-012-2657-z. Epub 2012 Sep 14. Ann Surg Oncol. 2013. PMID: 22976378
Increased risk for CRC in diabetic patients with the nonrisk allele of SNPs at 8q24.
Ishimaru S, Mimori K, Yamamoto K, Inoue H, Imoto S, Kawano S, Yamaguchi R, Sato T, Toh H, Iinuma H, Maeda T, Ishii H, Suzuki S, Tokudome S, Watanabe M, Tanaka J, Kudo SE, Sugihara K, Hase K, Mochizuki H, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Barnard GF, Miyano S, Mori M. Ishimaru S, et al. Among authors: sato t. Ann Surg Oncol. 2012 Sep;19(9):2853-8. doi: 10.1245/s10434-012-2278-6. Epub 2012 Mar 21. Ann Surg Oncol. 2012. PMID: 22434246
Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis.
Yokobori T, Iinuma H, Shimamura T, Imoto S, Sugimachi K, Ishii H, Iwatsuki M, Ota D, Ohkuma M, Iwaya T, Nishida N, Kogo R, Sudo T, Tanaka F, Shibata K, Toh H, Sato T, Barnard GF, Fukagawa T, Yamamoto S, Nakanishi H, Sasaki S, Miyano S, Watanabe T, Kuwano H, Mimori K, Pantel K, Mori M. Yokobori T, et al. Among authors: sato t. Cancer Res. 2013 Apr 1;73(7):2059-69. doi: 10.1158/0008-5472.CAN-12-0326. Epub 2013 Feb 1. Cancer Res. 2013. PMID: 23378342
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