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Nicotine induces cell proliferation in association with cyclin D1 up-regulation and inhibits cell differentiation in association with p53 regulation in a murine pre-osteoblastic cell line.
Sato T, Abe T, Nakamoto N, Tomaru Y, Koshikiya N, Nojima J, Kokabu S, Sakata Y, Kobayashi A, Yoda T. Sato T, et al. Biochem Biophys Res Commun. 2008 Dec 5;377(1):126-30. doi: 10.1016/j.bbrc.2008.09.114. Epub 2008 Oct 1. Biochem Biophys Res Commun. 2008. PMID: 18835254
The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation.
Kogawa M, Hisatake K, Atkins GJ, Findlay DM, Enoki Y, Sato T, Gray PC, Kanesaki-Yatsuka Y, Anderson PH, Wada S, Kato N, Fukuda A, Katayama S, Tsujimoto M, Yoda T, Suda T, Okazaki Y, Matsumoto M. Kogawa M, et al. Among authors: sato t. J Biol Chem. 2013 Oct 25;288(43):31299-312. doi: 10.1074/jbc.M113.461848. Epub 2013 Aug 29. J Biol Chem. 2013. PMID: 23990468 Free PMC article.
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