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A novel derivative (GTN024) from a natural product, komaroviquinone, induced the apoptosis of high-risk myeloma cells via reactive oxygen production and ER stress.
Okayama M, Kitabatake S, Sato M, Fujimori K, Ichikawa D, Matsushita M, Suto Y, Iwasaki G, Yamada T, Kiuchi F, Hirao M, Kunieda H, Osada M, Okamoto S, Hattori Y. Okayama M, et al. Among authors: sato m. Biochem Biophys Res Commun. 2018 Nov 2;505(3):787-793. doi: 10.1016/j.bbrc.2018.09.177. Epub 2018 Oct 5. Biochem Biophys Res Commun. 2018. PMID: 30297108
Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma.
Suto Y, Sato M, Fujimori K, Kitabatake S, Okayama M, Ichikawa D, Matsushita M, Yamagiwa N, Iwasaki G, Kiuchi F, Hattori Y. Suto Y, et al. Among authors: sato m. Bioorg Med Chem Lett. 2017 Oct 1;27(19):4558-4563. doi: 10.1016/j.bmcl.2017.08.054. Epub 2017 Aug 30. Bioorg Med Chem Lett. 2017. PMID: 28882484
Protocol for the nationwide registry of patients with polycystic kidney disease: japanese national registry of PKD (JRP).
Nakatani S, Kawano H, Sato M, Hoshino J, Nishio S, Miura K, Sekine A, Suwabe T, Hidaka S, Kataoka H, Ishikawa E, Shimazu K, Uchiyama K, Fujimaru T, Moriyama T, Kurashige M, Shimabukuro W, Hattanda F, Kimura T, Ushio Y, Manabe S, Watanabe H, Mitobe M, Seta K, Shimada Y, Kai H, Katayama K, Ichikawa D, Hayashi H, Hanaoka K, Mochizuki T, Nakanishi K, Tsuchiya K, Horie S, Isaka Y, Muto S; JRP collaborators. Nakatani S, et al. Among authors: sato m. Clin Exp Nephrol. 2024 May 11. doi: 10.1007/s10157-024-02509-3. Online ahead of print. Clin Exp Nephrol. 2024. PMID: 38734869
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