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Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites.
Breda C, Sathyasaikumar KV, Sograte Idrissi S, Notarangelo FM, Estranero JG, Moore GG, Green EW, Kyriacou CP, Schwarcz R, Giorgini F. Breda C, et al. Among authors: sathyasaikumar kv. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5435-40. doi: 10.1073/pnas.1604453113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114543 Free PMC article.
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.
Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P, Wu HQ, Lee J, Truong J, Andrews-Zwilling Y, Hsieh EW, Louie JY, Wu T, Scearce-Levie K, Patrick C, Adame A, Giorgini F, Moussaoui S, Laue G, Rassoulpour A, Flik G, Huang Y, Muchowski JM, Masliah E, Schwarcz R, Muchowski PJ. Zwilling D, et al. Among authors: sathyasaikumar kv. Cell. 2011 Jun 10;145(6):863-74. doi: 10.1016/j.cell.2011.05.020. Cell. 2011. PMID: 21640374 Free PMC article.
Drosophila eye color mutants as therapeutic tools for Huntington disease.
Green EW, Campesan S, Breda C, Sathyasaikumar KV, Muchowski PJ, Schwarcz R, Kyriacou CP, Giorgini F. Green EW, et al. Among authors: sathyasaikumar kv. Fly (Austin). 2012 Apr-Jun;6(2):117-20. doi: 10.4161/fly.19999. Epub 2012 Apr 1. Fly (Austin). 2012. PMID: 22634544
27 results