Sastre M - Search Results

1

Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease.

Rejc L, Gómez-Vallejo V, Joya A, Moreno O, Egimendia A, Castellnou P, Ríos-Anglada X, Cossío U, Baz Z, Passannante R, Tobalina-Larrea I, Ramos-Cabrer P, Giralt A, Sastre M, Capetillo-Zarate E, Košak U, Knez D, Gobec S, Marder M, Martin A, Llop J. Rejc L, et al. Among authors: sastre m. Theranostics. 2021 Apr 26;11(13):6542-6559. doi: 10.7150/thno.54589. eCollection 2021. Theranostics. 2021. PMID: 33995675 Free PMC article.

2

In vivo imaging of microglial activation by positron emission tomography with [(11)C]PBR28 in the 5XFAD model of Alzheimer's disease.

Mirzaei N, Tang SP, Ashworth S, Coello C, Plisson C, Passchier J, Selvaraj V, Tyacke RJ, Nutt DJ, Sastre M. Mirzaei N, et al. Among authors: sastre m. Glia. 2016 Jun;64(6):993-1006. doi: 10.1002/glia.22978. Epub 2016 Mar 9. Glia. 2016. PMID: 26959396

3

Imidazoline ligand BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease.

Mirzaei N, Mota BC, Birch AM, Davis N, Romero-Molina C, Katsouri L, Palmer EOC, Golbano A, Riggall LJ, Nagy I, Tyacke R, Nutt DJ, Sastre M. Mirzaei N, et al. Among authors: sastre m. Br J Pharmacol. 2021 Feb;178(3):654-671. doi: 10.1111/bph.15312. Epub 2020 Dec 27. Br J Pharmacol. 2021. PMID: 33140839 Free article.

4

Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease.

Katsouri L, Vizcaychipi MP, McArthur S, Harrison I, Suárez-Calvet M, Lleo A, Lloyd DG, Ma D, Sastre M. Katsouri L, et al. Among authors: sastre m. Neurobiol Aging. 2013 Apr;34(4):1105-15. doi: 10.1016/j.neurobiolaging.2012.09.010. Epub 2012 Oct 11. Neurobiol Aging. 2013. PMID: 23063647

5

Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer's disease.

Davis N, Mota BC, Stead L, Palmer EOC, Lombardero L, Rodríguez-Puertas R, de Paola V, Barnes SJ, Sastre M. Davis N, et al. Among authors: sastre m. J Neuroinflammation. 2021 Mar 17;18(1):73. doi: 10.1186/s12974-021-02117-y. J Neuroinflammation. 2021. PMID: 33731156 Free PMC article.

6

Astrocyte Reactivity in Alzheimer's Disease: Therapeutic Opportunities to Promote Repair.

Mirzaei N, Davis N, Chau TW, Sastre M. Mirzaei N, et al. Among authors: sastre m. Curr Alzheimer Res. 2022;19(1):1-15. doi: 10.2174/1567205018666211029164106. Curr Alzheimer Res. 2022. PMID: 34719372 Review.

7

Imaging of Microglial Activation in Alzheimer's Disease by [¹¹C]PBR28 PET.

Donat CK, Mirzaei N, Tang SP, Edison P, Sastre M. Donat CK, et al. Among authors: sastre m. Methods Mol Biol. 2018;1750:323-339. doi: 10.1007/978-1-4939-7704-8_22. Methods Mol Biol. 2018. PMID: 29512083

8

Ablation of reactive astrocytes exacerbates disease pathology in a model of Alzheimer's disease.

Katsouri L, Birch AM, Renziehausen AWJ, Zach C, Aman Y, Steeds H, Bonsu A, Palmer EOC, Mirzaei N, Ries M, Sastre M. Katsouri L, et al. Among authors: sastre m. Glia. 2020 May;68(5):1017-1030. doi: 10.1002/glia.23759. Epub 2019 Dec 4. Glia. 2020. PMID: 31799735 Free PMC article.

9

The Role of PGC1α in Alzheimer's Disease and Therapeutic Interventions.

Mota BC, Sastre M. Mota BC, et al. Among authors: sastre m. Int J Mol Sci. 2021 May 28;22(11):5769. doi: 10.3390/ijms22115769. Int J Mol Sci. 2021. PMID: 34071270 Free PMC article. Review.

10

In vivo Imaging of Glial Activation in Alzheimer's Disease.

Edison P, Donat CK, Sastre M. Edison P, et al. Among authors: sastre m. Front Neurol. 2018 Aug 7;9:625. doi: 10.3389/fneur.2018.00625. eCollection 2018. Front Neurol. 2018. PMID: 30131755 Free PMC article. Review.

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