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Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Herpes Simplex Oncolytic Virus.
Froechlich G, Caiazza C, Gentile C, D'Alise AM, De Lucia M, Langone F, Leoni G, Cotugno G, Scisciola V, Nicosia A, Scarselli E, Mallardo M, Sasso E, Zambrano N. Froechlich G, et al. Among authors: sasso e. Cancers (Basel). 2020 Nov 17;12(11):3407. doi: 10.3390/cancers12113407. Cancers (Basel). 2020. PMID: 33213060 Free PMC article.
Adenovirus Encoded Adjuvant (AdEnA) anti-CTLA-4, a novel strategy to improve Adenovirus based vaccines against infectious diseases and cancer.
D'Alise AM, Nocchi L, Garzia I, Seclì L, Infante L, Troise F, Cotugno G, Allocca S, Romano G, Lahm A, Leoni G, Sasso E, Scarselli E, Nicosia A. D'Alise AM, et al. Among authors: sasso e. Front Immunol. 2023 Apr 26;14:1156714. doi: 10.3389/fimmu.2023.1156714. eCollection 2023. Front Immunol. 2023. PMID: 37180141 Free PMC article.
The common H232 STING allele shows impaired activities in DNA sensing, susceptibility to viral infection, and in monocyte cell function, while the HAQ variant possesses wild-type properties.
Froechlich G, Finizio A, Napolano A, Amiranda S, De Chiara A, Pagano P, Mallardo M, Leoni G, Zambrano N, Sasso E. Froechlich G, et al. Among authors: sasso e. Sci Rep. 2023 Nov 9;13(1):19541. doi: 10.1038/s41598-023-46830-5. Sci Rep. 2023. PMID: 37945588 Free PMC article.
Prime and pull of T cell responses against cancer-exogenous antigens is effective against CPI-resistant tumors.
Troise F, Leoni G, Sasso E, Del Sorbo M, Esposito M, Romano G, Allocca S, Froechlich G, Cotugno G, Capone S, Folgori A, Scarselli E, D'Alise AM, Nicosia A. Troise F, et al. Among authors: sasso e. Mol Ther Oncol. 2024 Jan 10;32(1):200760. doi: 10.1016/j.omton.2024.200760. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596303 Free PMC article.
152 results