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Enhanced Hydrogen Bonding by Urea Functionalization Tunes the Stability and Biological Properties of Peptide Amphiphiles.
Xing H, Wigham C, Lee SR, Pereira AJ, de Campos LJ, Picco AS, Huck-Iriart C, Escudero C, Perez-Chirinos L, Gajaweera S, Comer J, Sasselli IR, Stupp SI, Zha RH, Conda-Sheridan M. Xing H, et al. Among authors: sasselli ir. Biomacromolecules. 2024 May 13;25(5):2823-2837. doi: 10.1021/acs.biomac.3c01463. Epub 2024 Apr 11. Biomacromolecules. 2024. PMID: 38602228
CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology.
Ortega JA, Sasselli IR, Boccitto M, Fleming AC, Fortuna TR, Li Y, Sato K, Clemons TD, Mckenna ED, Nguyen TP, Anderson EN, Asin J, Ichida JK, Pandey UB, Wolin SL, Stupp SI, Kiskinis E. Ortega JA, et al. Among authors: sasselli ir. Sci Adv. 2023 Nov 10;9(45):eadf7997. doi: 10.1126/sciadv.adf7997. Epub 2023 Nov 10. Sci Adv. 2023. PMID: 37948524 Free PMC article.
Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons.
Álvarez Z, Ortega JA, Sato K, Sasselli IR, Kolberg-Edelbrock AN, Qiu R, Marshall KA, Nguyen TP, Smith CS, Quinlan KA, Papakis V, Syrgiannis Z, Sather NA, Musumeci C, Engel E, Stupp SI, Kiskinis E. Álvarez Z, et al. Among authors: sasselli ir. Cell Stem Cell. 2023 Feb 2;30(2):219-238.e14. doi: 10.1016/j.stem.2022.12.010. Epub 2023 Jan 12. Cell Stem Cell. 2023. PMID: 36638801 Free PMC article.
Key aspects of the past 30 years of protein design.
Magi Meconi G, Sasselli IR, Bianco V, Onuchic JN, Coluzza I. Magi Meconi G, et al. Among authors: sasselli ir. Rep Prog Phys. 2022 Jul 6;85(8). doi: 10.1088/1361-6633/ac78ef. Rep Prog Phys. 2022. PMID: 35704983 Review.
24 results