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Ascl1-induced Wnt11 regulates neuroendocrine differentiation, cell proliferation, and E-cadherin expression in small-cell lung cancer and Wnt11 regulates small-cell lung cancer biology.
Tenjin Y, Kudoh S, Kubota S, Yamada T, Matsuo A, Sato Y, Ichimura T, Kohrogi H, Sashida G, Sakagami T, Ito T. Tenjin Y, et al. Among authors: sashida g. Lab Invest. 2019 Nov;99(11):1622-1635. doi: 10.1038/s41374-019-0277-y. Epub 2019 Jun 23. Lab Invest. 2019. PMID: 31231131 Free article.
Ezh2 loss propagates hypermethylation at T cell differentiation-regulating genes to promote leukemic transformation.
Wang C, Oshima M, Sato D, Matsui H, Kubota S, Aoyama K, Nakajima-Takagi Y, Koide S, Matsubayashi J, Mochizuki-Kashio M, Nakano-Yokomizo T, Bai J, Nagao T, Kanai A, Iwama A, Sashida G. Wang C, et al. Among authors: sashida g. J Clin Invest. 2018 Aug 31;128(9):3872-3886. doi: 10.1172/JCI94645. Epub 2018 Aug 6. J Clin Invest. 2018. PMID: 30080177 Free PMC article.
Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Kubota S, Tokunaga K, Umezu T, Yokomizo-Nakano T, Sun Y, Oshima M, Tan KT, Yang H, Kanai A, Iwanaga E, Asou N, Maeda T, Nakagata N, Iwama A, Ohyashiki K, Osato M, Sashida G. Kubota S, et al. Among authors: sashida g. Nat Commun. 2019 Apr 10;10(1):1653. doi: 10.1038/s41467-019-09710-z. Nat Commun. 2019. PMID: 30971697 Free PMC article.
Author Correction: Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Kubota S, Tokunaga K, Umezu T, Yokomizo-Nakano T, Sun Y, Oshima M, Tan KT, Yang H, Kanai A, Iwanaga E, Asou N, Maeda T, Nakagata N, Iwama A, Ohyashiki K, Osato M, Sashida G. Kubota S, et al. Among authors: sashida g. Nat Commun. 2019 Aug 28;10(1):3943. doi: 10.1038/s41467-019-11919-x. Nat Commun. 2019. PMID: 31462675 Free PMC article.
Calreticulin haploinsufficiency augments stem cell activity and is required for onset of myeloproliferative neoplasms in mice.
Shide K, Kameda T, Kamiunten A, Ozono Y, Tahira Y, Yokomizo-Nakano T, Kubota S, Ono M, Ikeda K, Sekine M, Akizuki K, Nakamura K, Hidaka T, Kubuki Y, Iwakiri H, Hasuike S, Nagata K, Sashida G, Shimoda K. Shide K, et al. Among authors: sashida g. Blood. 2020 Jul 2;136(1):106-118. doi: 10.1182/blood.2019003358. Blood. 2020. PMID: 32219445 Free PMC article.
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