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The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B4 axis.
Hosooka T, Hosokawa Y, Matsugi K, Shinohara M, Senga Y, Tamori Y, Aoki C, Matsui S, Sasaki T, Kitamura T, Kuroda M, Sakaue H, Nomura K, Yoshino K, Nabatame Y, Itoh Y, Yamaguchi K, Hayashi Y, Nakae J, Accili D, Yokomizo T, Seino S, Kasuga M, Ogawa W. Hosooka T, et al. Among authors: sasaki t. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11674-11684. doi: 10.1073/pnas.1921015117. Epub 2020 May 11. Proc Natl Acad Sci U S A. 2020. PMID: 32393635 Free PMC article.
Regulation of pancreatic juxtaductal endocrine cell formation by FoxO1.
Kitamura T, Kitamura YI, Kobayashi M, Kikuchi O, Sasaki T, Depinho RA, Accili D. Kitamura T, et al. Among authors: sasaki t. Mol Cell Biol. 2009 Aug;29(16):4417-30. doi: 10.1128/MCB.01622-08. Epub 2009 Jun 8. Mol Cell Biol. 2009. PMID: 19506018 Free PMC article.
FoxO1 as a double-edged sword in the pancreas: analysis of pancreas- and β-cell-specific FoxO1 knockout mice.
Kobayashi M, Kikuchi O, Sasaki T, Kim HJ, Yokota-Hashimoto H, Lee YS, Amano K, Kitazumi T, Susanti VY, Kitamura YI, Kitamura T. Kobayashi M, et al. Among authors: sasaki t. Am J Physiol Endocrinol Metab. 2012 Mar 1;302(5):E603-13. doi: 10.1152/ajpendo.00469.2011. Epub 2012 Jan 3. Am J Physiol Endocrinol Metab. 2012. PMID: 22215655 Free article.
9,161 results