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A landmark in drug discovery based on complex natural product synthesis.
Kawano S, Ito K, Yahata K, Kira K, Abe T, Akagi T, Asano M, Iso K, Sato Y, Matsuura F, Ohashi I, Matsumoto Y, Isomura M, Sasaki T, Fukuyama T, Miyashita Y, Kaburagi Y, Yokoi A, Asano O, Owa T, Kishi Y. Kawano S, et al. Among authors: sasaki t. Sci Rep. 2019 Jun 17;9(1):8656. doi: 10.1038/s41598-019-45001-9. Sci Rep. 2019. PMID: 31209263 Free PMC article.
Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials.
Kaburagi Y, Kira K, Yahata K, Iso K, Sato Y, Matsuura F, Ohashi I, Matsumoto Y, Isomura M, Sasaki T, Fukuyama T, Miyashita Y, Azuma H, Iida D, Ishida T, Itano W, Matsuda M, Matsukura M, Murai N, Nagao S, Seki M, Yamamoto A, Yamamoto Y, Yoneda N, Watanabe Y, Kamada A, Kayano A, Tagami K, Asano O, Owa T, Kishi Y. Kaburagi Y, et al. Among authors: sasaki t. Org Lett. 2024 Apr 12;26(14):2837-2842. doi: 10.1021/acs.orglett.3c03663. Epub 2024 Jan 22. Org Lett. 2024. PMID: 38252895
Development of a laparoscopic sigmoidectomy simulator: Sigmaster.
Shigaki T, Hasegawa H, Teramura K, Takeshita N, Ikeda K, Tsukada Y, Nishizawa Y, Sasaki T, Ito M. Shigaki T, et al. Among authors: sasaki t. Surg Today. 2024 May 14. doi: 10.1007/s00595-024-02855-5. Online ahead of print. Surg Today. 2024. PMID: 38740574
A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion.
Kofuji S, Wolfe K, Sumita K, Kageyama S, Yoshino H, Hirota Y, Ogawa-Iio A, Kanoh H, Sasaki M, Kofuji K, Davis MI, Pragani R, Shen M, Boxer MB, Nakatsu F, Nigorikawa K, Sasaki T, Takeuchi K, Senda T, Kim SM, Edinger AL, Simeonov A, Sasaki AT. Kofuji S, et al. Among authors: sasaki t. Biochem Biophys Res Commun. 2024 Apr 27;718:149981. doi: 10.1016/j.bbrc.2024.149981. Online ahead of print. Biochem Biophys Res Commun. 2024. PMID: 38735134
9,165 results