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Page 1
New and emerging technologies for genetic toxicity testing.
Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A Jr, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH. Lynch AM, et al. Among authors: sasaki jc. Environ Mol Mutagen. 2011 Apr;52(3):205-23. doi: 10.1002/em.20614. Epub 2010 Aug 25. Environ Mol Mutagen. 2011. PMID: 20740635 Review.
Application of the adverse outcome pathway framework to genotoxic modes of action.
Sasaki JC, Allemang A, Bryce SM, Custer L, Dearfield KL, Dietz Y, Elhajouji A, Escobar PA, Fornace AJ Jr, Froetschl R, Galloway S, Hemmann U, Hendriks G, Li HH, Luijten M, Ouedraogo G, Peel L, Pfuhler S, Roberts DJ, Thybaud V, van Benthem J, Yauk CL, Schuler M. Sasaki JC, et al. Environ Mol Mutagen. 2020 Jan;61(1):114-134. doi: 10.1002/em.22339. Epub 2019 Oct 31. Environ Mol Mutagen. 2020. PMID: 31603995
Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses.
Amberg A, Andaya RV, Anger LT, Barber C, Beilke L, Bercu J, Bower D, Brigo A, Cammerer Z, Cross KP, Custer L, Dobo K, Gerets H, Gervais V, Glowienke S, Gomez S, Van Gompel J, Harvey J, Hasselgren C, Honma M, Johnson C, Jolly R, Kemper R, Kenyon M, Kruhlak N, Leavitt P, Miller S, Muster W, Naven R, Nicolette J, Parenty A, Powley M, Quigley DP, Reddy MV, Sasaki JC, Stavitskaya L, Teasdale A, Trejo-Martin A, Weiner S, Welch DS, White A, Wichard J, Woolley D, Myatt GJ. Amberg A, et al. Among authors: sasaki jc. Regul Toxicol Pharmacol. 2019 Mar;102:53-64. doi: 10.1016/j.yrtph.2018.12.007. Epub 2018 Dec 15. Regul Toxicol Pharmacol. 2019. PMID: 30562600 Free PMC article.
Utility of a next-generation framework for assessment of genomic damage: A case study using the pharmaceutical drug candidate etoposide.
Nicolette J, Luijten M, Sasaki JC, Custer L, Embry M, Froetschl R, Johnson G, Ouedraogo G, Settivari R, Thybaud V, Dearfield KL. Nicolette J, et al. Among authors: sasaki jc. Environ Mol Mutagen. 2021 Nov;62(9):512-525. doi: 10.1002/em.22467. Epub 2021 Nov 22. Environ Mol Mutagen. 2021. PMID: 34775645 Free PMC article. Review.
Biocompatible anti-aging face mask prepared with curcumin and natural rubber with antioxidant properties.
de Souza Silva FK, Costa-Orlandi CB, Fernandes MA, Pegorin Brasil GS, Mussagy CU, Scontri M, Sasaki JCDS, de Sousa Abreu AP, Guerra NB, Floriano JF, de Mendonça RJ, Caetano GF, Farhadi N, Gómez A, Huang S, Farias AM, Primo FL, Li B, Fusco-Almeida AM, Dokmeci MR, Jucaud V, Mendes-Giannini MJS, Cardoso MR, Herculano RD. de Souza Silva FK, et al. Among authors: sasaki jcds. Int J Biol Macromol. 2023 Jul 1;242(Pt 1):124778. doi: 10.1016/j.ijbiomac.2023.124778. Epub 2023 May 10. Int J Biol Macromol. 2023. PMID: 37172704
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease.
Jennings D, Huntwork-Rodriguez S, Henry AG, Sasaki JC, Meisner R, Diaz D, Solanoy H, Wang X, Negrou E, Bondar VV, Ghosh R, Maloney MT, Propson NE, Zhu Y, Maciuca RD, Harris L, Kay A, LeWitt P, King TA, Kern D, Ellenbogen A, Goodman I, Siderowf A, Aldred J, Omidvar O, Masoud ST, Davis SS, Arguello A, Estrada AA, de Vicente J, Sweeney ZK, Astarita G, Borin MT, Wong BK, Wong H, Nguyen H, Scearce-Levie K, Ho C, Troyer MD. Jennings D, et al. Among authors: sasaki jc. Sci Transl Med. 2022 Jun 8;14(648):eabj2658. doi: 10.1126/scitranslmed.abj2658. Epub 2022 Jun 8. Sci Transl Med. 2022. PMID: 35675433
ABC gene-ranking for prediction of drug-induced cholestasis in rats.
Cherkas Y, McMillian MK, Amaratunga D, Raghavan N, Sasaki JC. Cherkas Y, et al. Among authors: sasaki jc. Toxicol Rep. 2016 Jan 18;3:252-261. doi: 10.1016/j.toxrep.2016.01.009. eCollection 2016. Toxicol Rep. 2016. PMID: 28959545 Free PMC article.
18 results