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Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells.
Ikeda Y, Davis MI, Sumita K, Zheng Y, Kofuji S, Sasaki M, Hirota Y, Pragani R, Shen M, Boxer MB, Takeuchi K, Senda T, Simeonov A, Sasaki AT. Ikeda Y, et al. Among authors: sasaki at. Biochem Biophys Res Commun. 2023 Oct 30;679:116-121. doi: 10.1016/j.bbrc.2023.08.050. Epub 2023 Aug 26. Biochem Biophys Res Commun. 2023. PMID: 37683456 Free article.
The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.
Sumita K, Lo YH, Takeuchi K, Senda M, Kofuji S, Ikeda Y, Terakawa J, Sasaki M, Yoshino H, Majd N, Zheng Y, Kahoud ER, Yokota T, Emerling BM, Asara JM, Ishida T, Locasale JW, Daikoku T, Anastasiou D, Senda T, Sasaki AT. Sumita K, et al. Among authors: sasaki m, sasaki at. Mol Cell. 2016 Jan 21;61(2):187-98. doi: 10.1016/j.molcel.2015.12.011. Epub 2016 Jan 7. Mol Cell. 2016. PMID: 26774281 Free PMC article.
Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ.
Takeuchi K, Senda M, Ikeda Y, Okuwaki K, Fukuzawa K, Nakagawa S, Sasaki M, Sasaki AT, Senda T. Takeuchi K, et al. Among authors: sasaki at. FEBS J. 2023 Sep;290(18):4419-4428. doi: 10.1111/febs.16763. Epub 2023 Mar 10. FEBS J. 2023. PMID: 36856076 Free PMC article.
Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors.
Manz TD, Sivakumaren SC, Yasgar A, Hall MD, Davis MI, Seo HS, Card JD, Ficarro SB, Shim H, Marto JA, Dhe-Paganon S, Sasaki AT, Boxer MB, Simeonov A, Cantley LC, Shen M, Zhang T, Ferguson FM, Gray NS. Manz TD, et al. Among authors: sasaki at. ACS Med Chem Lett. 2019 Nov 3;11(3):346-352. doi: 10.1021/acsmedchemlett.9b00402. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184968 Free PMC article.
83 results