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Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival.
Segatto M, Fittipaldi R, Pin F, Sartori R, Dae Ko K, Zare H, Fenizia C, Zanchettin G, Pierobon ES, Hatakeyama S, Sperti C, Merigliano S, Sandri M, Filippakopoulos P, Costelli P, Sartorelli V, Caretti G. Segatto M, et al. Among authors: sartori r. Nat Commun. 2017 Nov 22;8(1):1707. doi: 10.1038/s41467-017-01645-7. Nat Commun. 2017. PMID: 29167426 Free PMC article.
Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia.
Sartori R, Hagg A, Zampieri S, Armani A, Winbanks CE, Viana LR, Haidar M, Watt KI, Qian H, Pezzini C, Zanganeh P, Turner BJ, Larsson A, Zanchettin G, Pierobon ES, Moletta L, Valmasoni M, Ponzoni A, Attar S, Da Dalt G, Sperti C, Kustermann M, Thomson RE, Larsson L, Loveland KL, Costelli P, Megighian A, Merigliano S, Penna F, Gregorevic P, Sandri M. Sartori R, et al. Sci Transl Med. 2021 Aug 4;13(605):eaay9592. doi: 10.1126/scitranslmed.aay9592. Sci Transl Med. 2021. PMID: 34349036
The ERG1A K+ Channel Is More Abundant in Rectus abdominis Muscle from Cancer Patients Than that from Healthy Humans.
Zampieri S, Sandri M, Cheatwood JL, Balaraman RP, Anderson LB, Cobb BA, Latour CD, Hockerman GH, Kern H, Sartori R, Ravara B, Merigliano S, Da Dalt G, Davie JK, Kohli P, Pond AL. Zampieri S, et al. Among authors: sartori r. Diagnostics (Basel). 2021 Oct 12;11(10):1879. doi: 10.3390/diagnostics11101879. Diagnostics (Basel). 2021. PMID: 34679577 Free PMC article.
Activation of Akt-mTORC1 signalling reverts cancer-dependent muscle wasting.
Geremia A, Sartori R, Baraldo M, Nogara L, Balmaceda V, Dumitras GA, Ciciliot S, Scalabrin M, Nolte H, Blaauw B. Geremia A, et al. Among authors: sartori r. J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):648-661. doi: 10.1002/jcsm.12854. Epub 2021 Nov 6. J Cachexia Sarcopenia Muscle. 2022. PMID: 34741441 Free PMC article.
Plasma proteome profiling of healthy subjects undergoing bed rest reveals unloading-dependent changes linked to muscle atrophy.
Murgia M, Brocca L, Monti E, Franchi MV, Zwiebel M, Steigerwald S, Giacomello E, Sartori R, Zampieri S, Capovilla G, Gasparini M, Biolo G, Sandri M, Mann M, Narici MV. Murgia M, et al. Among authors: sartori r. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):439-451. doi: 10.1002/jcsm.13146. Epub 2022 Dec 14. J Cachexia Sarcopenia Muscle. 2023. PMID: 36517414 Free PMC article.
NAD+ repletion with niacin counteracts cancer cachexia.
Beltrà M, Pöllänen N, Fornelli C, Tonttila K, Hsu MY, Zampieri S, Moletta L, Corrà S, Porporato PE, Kivelä R, Viscomi C, Sandri M, Hulmi JJ, Sartori R, Pirinen E, Penna F. Beltrà M, et al. Among authors: sartori r. Nat Commun. 2023 Apr 3;14(1):1849. doi: 10.1038/s41467-023-37595-6. Nat Commun. 2023. PMID: 37012289 Free PMC article.
Smad2 and 3 transcription factors control muscle mass in adulthood.
Sartori R, Milan G, Patron M, Mammucari C, Blaauw B, Abraham R, Sandri M. Sartori R, et al. Am J Physiol Cell Physiol. 2009 Jun;296(6):C1248-57. doi: 10.1152/ajpcell.00104.2009. Epub 2009 Apr 8. Am J Physiol Cell Physiol. 2009. PMID: 19357234 Free article.
281 results