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Modulation of the Passive Permeability of Semipeptidic Macrocycles: N- and C-Methylations Fine-Tune Conformation and Properties.
Comeau C, Ries B, Stadelmann T, Tremblay J, Poulet S, Fröhlich U, Côté J, Boudreault PL, Derbali RM, Sarret P, Grandbois M, Leclair G, Riniker S, Marsault É. Comeau C, et al. Among authors: sarret p. J Med Chem. 2021 May 13;64(9):5365-5383. doi: 10.1021/acs.jmedchem.0c02036. Epub 2021 Mar 22. J Med Chem. 2021. PMID: 33750117
Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions.
Murza A, Sainsily X, Coquerel D, Côté J, Marx P, Besserer-Offroy É, Longpré JM, Lainé J, Reversade B, Salvail D, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É. Murza A, et al. Among authors: sarret p. J Med Chem. 2016 Apr 14;59(7):2962-72. doi: 10.1021/acs.jmedchem.5b01549. Epub 2016 Mar 30. J Med Chem. 2016. PMID: 26986036
The signaling signature of the neurotensin type 1 receptor with endogenous ligands.
Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R. Besserer-Offroy É, et al. Among authors: sarret p. Eur J Pharmacol. 2017 Jun 15;805:1-13. doi: 10.1016/j.ejphar.2017.03.046. Epub 2017 Mar 22. Eur J Pharmacol. 2017. PMID: 28341345
Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues.
Fanelli R, Floquet N, Besserer-Offroy É, Delort B, Vivancos M, Longpré JM, Renault P, Martinez J, Sarret P, Cavelier F. Fanelli R, et al. Among authors: sarret p. J Med Chem. 2017 Apr 27;60(8):3303-3313. doi: 10.1021/acs.jmedchem.6b01848. Epub 2017 Apr 10. J Med Chem. 2017. PMID: 28368584
144 results