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Dual Relief of T-lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies.
Balança CC, Scarlata CM, Michelas M, Devaud C, Sarradin V, Franchet C, Martinez Gomez C, Gomez-Roca C, Tosolini M, Heaugwane D, Lauzéral-Vizcaino F, Mir-Mesnier L, Féliu V, Valle C, Pont F, Ferron G, Gladieff L, Motton S, Tanguy Le Gac Y, Dupret-Bories A, Sarini J, Vairel B, Illac C, Siegfried-Vergnon A, Mery E, Fournié JJ, Vergez S, Delord JP, Rochaix P, Martinez A, Ayyoub M. Balança CC, et al. Among authors: sarradin v. Cancer Immunol Res. 2020 Jul;8(7):869-882. doi: 10.1158/2326-6066.CIR-19-0855. Epub 2020 Apr 15. Cancer Immunol Res. 2020. PMID: 32295784
PD-1 blockade restores helper activity of tumor-infiltrating, exhausted PD-1hiCD39+ CD4 T cells.
Balança CC, Salvioni A, Scarlata CM, Michelas M, Martinez-Gomez C, Gomez-Roca C, Sarradin V, Tosolini M, Valle C, Pont F, Ferron G, Gladieff L, Vergez S, Dupret-Bories A, Mery E, Rochaix P, Fournié JJ, Delord JP, Devaud C, Martinez A, Ayyoub M. Balança CC, et al. Among authors: sarradin v. JCI Insight. 2021 Jan 25;6(2):e142513. doi: 10.1172/jci.insight.142513. JCI Insight. 2021. PMID: 33332284 Free PMC article.
Circulating Exhausted PD-1+CD39+ Helper CD4 T Cells Are Tumor-Antigen-Specific and Predict Response to PD-1/PD-L1 Axis Blockade.
Martinez-Gomez C, Michelas M, Scarlata CM, Salvioni A, Gomez-Roca C, Sarradin V, Lauzéral-Vizcaino F, Féliu V, Dupret-Bories A, Ferron G, Sarini J, Devaud C, Delord JP, Balança CC, Martinez A, Ayyoub M. Martinez-Gomez C, et al. Among authors: sarradin v. Cancers (Basel). 2022 Jul 28;14(15):3679. doi: 10.3390/cancers14153679. Cancers (Basel). 2022. PMID: 35954341 Free PMC article.
12 results