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Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2).
Cocco E, Javier Carmona F, Razavi P, Won HH, Cai Y, Rossi V, Chan C, Cownie J, Soong J, Toska E, Shifman SG, Sarotto I, Savas P, Wick MJ, Papadopoulos KP, Moriarty A, Cutler RE Jr, Avogadri-Connors F, Lalani AS, Bryce RP, Chandarlapaty S, Hyman DM, Solit DB, Boni V, Loi S, Baselga J, Berger MF, Montemurro F, Scaltriti M. Cocco E, et al. Among authors: sarotto i. Sci Signal. 2018 Oct 9;11(551):eaat9773. doi: 10.1126/scisignal.aat9773. Sci Signal. 2018. PMID: 30301790 Free PMC article.
TGFalpha expression impairs Trastuzumab-induced HER2 downregulation.
Valabrega G, Montemurro F, Sarotto I, Petrelli A, Rubini P, Tacchetti C, Aglietta M, Comoglio PM, Giordano S. Valabrega G, et al. Among authors: sarotto i. Oncogene. 2005 Apr 21;24(18):3002-10. doi: 10.1038/sj.onc.1208478. Oncogene. 2005. PMID: 15735715
Correlations between diffusion-weighted imaging and breast cancer biomarkers.
Martincich L, Deantoni V, Bertotto I, Redana S, Kubatzki F, Sarotto I, Rossi V, Liotti M, Ponzone R, Aglietta M, Regge D, Montemurro F. Martincich L, et al. Among authors: sarotto i. Eur Radiol. 2012 Jul;22(7):1519-28. doi: 10.1007/s00330-012-2403-8. Epub 2012 Mar 13. Eur Radiol. 2012. PMID: 22411304
Omission of axillary dissection after a positive sentinel node dissection may influence adjuvant chemotherapy indications in operable breast cancer patients.
Montemurro F, Maggiorotto F, Valabrega G, Kubatzki F, Rossi V, Magistris A, Marocco F, Gatti M, Sarotto I, Aglietta M, Ponzone R. Montemurro F, et al. Among authors: sarotto i. Ann Surg Oncol. 2012 Nov;19(12):3755-61. doi: 10.1245/s10434-012-2505-1. Epub 2012 Jul 18. Ann Surg Oncol. 2012. PMID: 22805871
Moderate immunohistochemical expression of HER-2 (2+) without HER-2 gene amplification is a negative prognostic factor in early breast cancer.
Rossi V, Sarotto I, Maggiorotto F, Berchialla P, Kubatzki F, Tomasi N, Redana S, Martinello R, Valabrega G, Aglietta M, Ponzone R, Montemurro F. Rossi V, et al. Among authors: sarotto i. Oncologist. 2012;17(11):1418-25. doi: 10.1634/theoncologist.2012-0194. Epub 2012 Sep 4. Oncologist. 2012. PMID: 22951668 Free PMC article.
54 results