Sarkaria JN - Search Results

1

Inhibiting DNA-PK_CS radiosensitizes human osteosarcoma cells.

Mamo T, Mladek AC, Shogren KL, Gustafson C, Gupta SK, Riester SM, Maran A, Galindo M, van Wijnen AJ, Sarkaria JN, Yaszemski MJ. Mamo T, et al. Among authors: sarkaria jn. Biochem Biophys Res Commun. 2017 Apr 29;486(2):307-313. doi: 10.1016/j.bbrc.2017.03.033. Epub 2017 Mar 12. Biochem Biophys Res Commun. 2017. PMID: 28300555 Free PMC article.

2

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.

Sarkaria JN, Tibbetts RS, Busby EC, Kennedy AP, Hill DE, Abraham RT. Sarkaria JN, et al. Cancer Res. 1998 Oct 1;58(19):4375-82. Cancer Res. 1998. PMID: 9766667

3

The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1.

Busby EC, Leistritz DF, Abraham RT, Karnitz LM, Sarkaria JN. Busby EC, et al. Among authors: sarkaria jn. Cancer Res. 2000 Apr 15;60(8):2108-12. Cancer Res. 2000. PMID: 10786669

4

Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy.

Eshleman JS, Carlson BL, Mladek AC, Kastner BD, Shide KL, Sarkaria JN. Eshleman JS, et al. Among authors: sarkaria jn. Cancer Res. 2002 Dec 15;62(24):7291-7. Cancer Res. 2002. PMID: 12499272

5

Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells.

Rao RD, Mladek AC, Lamont JD, Goble JM, Erlichman C, James CD, Sarkaria JN. Rao RD, et al. Among authors: sarkaria jn. Neoplasia. 2005 Oct;7(10):921-9. doi: 10.1593/neo.05361. Neoplasia. 2005. PMID: 16242075 Free PMC article.

6

Phase I trial of sirolimus combined with radiation and cisplatin in non-small cell lung cancer.

Sarkaria JN, Schwingler P, Schild SE, Grogan PT, Mladek AC, Mandrekar SJ, Tan AD, Kobayashi T, Marks RS, Kita H, Miller RC, Limper AH, Leof EB. Sarkaria JN, et al. J Thorac Oncol. 2007 Aug;2(8):751-7. doi: 10.1097/JTO.0b013e3180cc2587. J Thorac Oncol. 2007. PMID: 17762343 Free article. Clinical Trial.

7

Using fluorodeoxythymidine to monitor anti-EGFR inhibitor therapy in squamous cell carcinoma xenografts.

Atkinson DM, Clarke MJ, Mladek AC, Carlson BL, Trump DP, Jacobson MS, Kemp BJ, Lowe VJ, Sarkaria JN. Atkinson DM, et al. Among authors: sarkaria jn. Head Neck. 2008 Jun;30(6):790-9. doi: 10.1002/hed.20770. Head Neck. 2008. PMID: 18286491 Free PMC article.

8

PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel.

Yang L, Clarke MJ, Carlson BL, Mladek AC, Schroeder MA, Decker P, Wu W, Kitange GJ, Grogan PT, Goble JM, Uhm J, Galanis E, Giannini C, Lane HA, James CD, Sarkaria JN. Yang L, et al. Among authors: sarkaria jn. Clin Cancer Res. 2008 Jun 15;14(12):3993-4001. doi: 10.1158/1078-0432.CCR-07-4152. Clin Cancer Res. 2008. PMID: 18559622 Free PMC article.

9

Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model.

Kitange GJ, Carlson BL, Mladek AC, Decker PA, Schroeder MA, Wu W, Grogan PT, Giannini C, Ballman KV, Buckner JC, James CD, Sarkaria JN. Kitange GJ, et al. Among authors: sarkaria jn. J Neurooncol. 2009 Mar;92(1):23-31. doi: 10.1007/s11060-008-9737-8. Epub 2008 Nov 15. J Neurooncol. 2009. PMID: 19011762 Free PMC article.

10

Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines.

Clarke MJ, Mulligan EA, Grogan PT, Mladek AC, Carlson BL, Schroeder MA, Curtin NJ, Lou Z, Decker PA, Wu W, Plummer ER, Sarkaria JN. Clarke MJ, et al. Among authors: sarkaria jn. Mol Cancer Ther. 2009 Feb;8(2):407-14. doi: 10.1158/1535-7163.MCT-08-0854. Epub 2009 Jan 27. Mol Cancer Ther. 2009. PMID: 19174557 Free PMC article.

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