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Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cruz-Lopez O, Lopez Cara C, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Gambari R, Ilaria L, Saletti R, Brancale A, Hamel E. Romagnoli R, et al. Among authors: sarkar t. Bioorg Med Chem. 2008 Sep 15;16(18):8419-26. doi: 10.1016/j.bmc.2008.08.029. Epub 2008 Aug 17. Bioorg Med Chem. 2008. PMID: 18755591 Free PMC article.
Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Hsieh HP, Hamel E. Romagnoli R, et al. Among authors: sarkar t. J Med Chem. 2008 Mar 13;51(5):1464-8. doi: 10.1021/jm7011547. Epub 2008 Feb 9. J Med Chem. 2008. PMID: 18260616
Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Among authors: sarkar t. Bioorg Med Chem. 2008 May 15;16(10):5367-76. doi: 10.1016/j.bmc.2008.04.026. Epub 2008 Apr 15. Bioorg Med Chem. 2008. PMID: 18440234
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-6-substituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Cruz-Lopez O, Cara CL, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Kandil S, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Among authors: sarkar t. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5041-5. doi: 10.1016/j.bmcl.2008.08.006. Epub 2008 Aug 6. Bioorg Med Chem Lett. 2008. PMID: 18725179 Free PMC article.
New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.
La Regina G, Sarkar T, Bai R, Edler MC, Saletti R, Coluccia A, Piscitelli F, Minelli L, Gatti V, Mazzoccoli C, Palermo V, Mazzoni C, Falcone C, Scovassi AI, Giansanti V, Campiglia P, Porta A, Maresca B, Hamel E, Brancale A, Novellino E, Silvestri R. La Regina G, et al. Among authors: sarkar t. J Med Chem. 2009 Dec 10;52(23):7512-27. doi: 10.1021/jm900016t. J Med Chem. 2009. PMID: 19601594 Free PMC article.
Inhibition of tubulin polymerization by select alkenyldiarylmethanes.
Cullen MD, Sarkar T, Hamel E, Hartman TL, Watson KM, Buckheit RW Jr, Pannecouque C, De Clercq E, Cushman M. Cullen MD, et al. Among authors: sarkar t. Bioorg Med Chem Lett. 2008 Jan 15;18(2):469-73. doi: 10.1016/j.bmcl.2007.11.114. Epub 2007 Dec 4. Bioorg Med Chem Lett. 2008. PMID: 18083556 Free PMC article.
610 results