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An insulin-regulated arrestin domain protein controls hepatic glucagon action.
Dagdeviren S, Hoang MF, Sarikhani M, Meier V, Benoit JC, Okawa MC, Melnik VY, Ricci-Blair EM, Foot N, Friedline RH, Hu X, Tauer LA, Srinivasan A, Prigozhin MB, Shenoy SK, Kumar S, Kim JK, Lee RT. Dagdeviren S, et al. Among authors: sarikhani m. J Biol Chem. 2023 Aug;299(8):105045. doi: 10.1016/j.jbc.2023.105045. Epub 2023 Jul 13. J Biol Chem. 2023. PMID: 37451484 Free PMC article.
Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence.
Garbern JC, Helman A, Sereda R, Sarikhani M, Ahmed A, Escalante GO, Ogurlu R, Kim SL, Zimmerman JF, Cho A, MacQueen L, Bezzerides VJ, Parker KK, Melton DA, Lee RT. Garbern JC, et al. Among authors: sarikhani m. Circulation. 2020 Jan 28;141(4):285-300. doi: 10.1161/CIRCULATIONAHA.119.044205. Epub 2019 Nov 11. Circulation. 2020. PMID: 31707831 Free PMC article.
Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice.
Spurthi KM, Sarikhani M, Mishra S, Desingu PA, Yadav S, Rao S, Maity S, Tamta AK, Kumar S, Majumdar S, Jain A, Raghuraman A, Khan D, Singh I, Samuel RJ, Ramachandra SG, Nandi D, Sundaresan NR. Spurthi KM, et al. Among authors: sarikhani m. J Biol Chem. 2018 Aug 24;293(34):13073-13089. doi: 10.1074/jbc.RA118.001880. Epub 2018 Jun 21. J Biol Chem. 2018. PMID: 29929978 Free PMC article.
SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis.
Sarikhani M, Maity S, Mishra S, Jain A, Tamta AK, Ravi V, Kondapalli MS, Desingu PA, Khan D, Kumar S, Rao S, Inbaraj M, Pandit AS, Sundaresan NR. Sarikhani M, et al. J Biol Chem. 2018 Apr 6;293(14):5281-5294. doi: 10.1074/jbc.RA117.000915. Epub 2018 Feb 13. J Biol Chem. 2018. PMID: 29440391 Free PMC article.
Nitric oxide synthase 2 enhances the survival of mice during Salmonella Typhimurium infection-induced sepsis by increasing reactive oxygen species, inflammatory cytokines and recruitment of neutrophils to the peritoneal cavity.
Yadav S, Pathak S, Sarikhani M, Majumdar S, Ray S, Chandrasekar BS, Adiga V, Sundaresan NR, Nandi D. Yadav S, et al. Among authors: sarikhani m. Free Radic Biol Med. 2018 Feb 20;116:73-87. doi: 10.1016/j.freeradbiomed.2017.12.032. Epub 2018 Jan 5. Free Radic Biol Med. 2018. PMID: 29309892
SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity.
Ravi V, Jain A, Khan D, Ahamed F, Mishra S, Giri M, Inbaraj M, Krishna S, Sarikhani M, Maity S, Kumar S, Shah RA, Dave P, Pandit AS, Rajendran R, Desingu PA, Varshney U, Das S, Kolthur-Seetharam U, Rajakumari S, Singh M, Sundaresan NR. Ravi V, et al. Among authors: sarikhani m. Nucleic Acids Res. 2019 Sep 26;47(17):9115-9131. doi: 10.1093/nar/gkz648. Nucleic Acids Res. 2019. PMID: 31372634 Free PMC article.
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