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Quantitative evaluation of trastuzumab deruxtecan pharmacokinetics and pharmacodynamics in mouse models of varying degrees of HER2 expression.
Vasalou C, Proia TA, Kazlauskas L, Przybyla A, Sung M, Mamidi S, Maratea K, Griffin M, Sargeant R, Urosevic J, Rosenbaum AI, Yuan J, Aluri KC, Ramsden D, Hariparsad N, Jones RDO, Mettetal JT. Vasalou C, et al. Among authors: sargeant r. CPT Pharmacometrics Syst Pharmacol. 2024 Mar 26. doi: 10.1002/psp4.13133. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38532525 Free article.
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function.
Asowata EO, Romoli S, Sargeant R, Tan JY, Hoffmann S, Huang MM, Mahbubani KT, Krause FN, Jachimowicz D, Agren R, Koulman A, Jenkins B, Musial B, Griffin JL, Soderberg M, Ling S, Hansen PBL, Saeb-Parsy K, Woollard KJ. Asowata EO, et al. Among authors: sargeant r. Kidney Int. 2024 Feb 29:S0085-2538(24)00168-6. doi: 10.1016/j.kint.2024.01.041. Online ahead of print. Kidney Int. 2024. PMID: 38431215 Free article.
Mass Spectrometry Detection and Imaging of a Non-Covalent Protein-Drug Complex in Tissue from Orally Dosed Rats.
Illes-Toth E, Hale OJ, Hughes JW, Strittmatter N, Rose J, Clayton B, Sargeant R, Jones S, Dannhorn A, Goodwin RJA, Cooper HJ. Illes-Toth E, et al. Among authors: sargeant r. Angew Chem Weinheim Bergstr Ger. 2022 Sep 5;134(36):e202202075. doi: 10.1002/ange.202202075. Epub 2022 Jul 13. Angew Chem Weinheim Bergstr Ger. 2022. PMID: 38505542 Free PMC article.
Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells.
Matthews O, Morrison EE, Tranter JD, Starkey Lewis P, Toor IS, Srivastava A, Sargeant R, Rollison H, Matchett KP, Kendall TJ, Gray GA, Goldring C, Park K, Denby L, Dhaun N, Bailey MA, Henderson NC, Williams D, Dear JW. Matthews O, et al. Among authors: sargeant r. EBioMedicine. 2020 Dec;62:103092. doi: 10.1016/j.ebiom.2020.103092. Epub 2020 Nov 21. EBioMedicine. 2020. PMID: 33232872 Free PMC article.
46 results