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NOX2 control over energy metabolism plays a role in acute myeloid leukaemia prognosis and survival.
Ijurko C, Romo-González M, García-Calvo C, Sardina JL, Sánchez-Bernal C, Sánchez-Yagüe J, Elena-Herrmann B, Villaret J, Garrel C, Mondet J, Mossuz P, Hernández-Hernández Á. Ijurko C, et al. Among authors: sardina jl. Free Radic Biol Med. 2023 Nov 20;209(Pt 1):18-28. doi: 10.1016/j.freeradbiomed.2023.10.013. Epub 2023 Oct 6. Free Radic Biol Med. 2023. PMID: 37806599 Free article.
p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response.
Serra F, Nieto-Aliseda A, Fanlo-Escudero L, Rovirosa L, Cabrera-Pasadas M, Lazarenkov A, Urmeneta B, Alcalde-Merino A, Nola EM, Okorokov AL, Fraser P, Graupera M, Castillo SD, Sardina JL, Valencia A, Javierre BM. Serra F, et al. Among authors: sardina jl. Nat Commun. 2024 Apr 1;15(1):2821. doi: 10.1038/s41467-024-46666-1. Nat Commun. 2024. PMID: 38561401 Free PMC article.
The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte development.
Azagra A, Meler A, de Barrios O, Tomás-Daza L, Collazo O, Monterde B, Obiols M, Rovirosa L, Vila-Casadesús M, Cabrera-Pasadas M, Gusi-Vives M, Graf T, Varela I, Sardina JL, Javierre BM, Parra M. Azagra A, et al. Among authors: sardina jl. Nucleic Acids Res. 2022 Aug 26;50(15):8471-8490. doi: 10.1093/nar/gkac619. Nucleic Acids Res. 2022. PMID: 35904805 Free PMC article.
Editorial: Chromatin Regulation in Cell Fate Decisions.
Brumbaugh J, Di Stefano B, Sardina JL. Brumbaugh J, et al. Among authors: sardina jl. Front Cell Dev Biol. 2021 Sep 1;9:734020. doi: 10.3389/fcell.2021.734020. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34540846 Free PMC article. No abstract available.
Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion.
Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury J, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan J, Habelhah H, Waldschmidt T, Müschen M, Bagg A, Darbro B, Zhao C. Xiu Y, et al. Among authors: sardina jl. Blood. 2020 Jan 9;135(2):108-120. doi: 10.1182/blood.2019001438. Blood. 2020. PMID: 31697816 Free PMC article.
Whsc1 links pluripotency exit with mesendoderm specification.
Tian TV, Di Stefano B, Stik G, Vila-Casadesús M, Sardina JL, Vidal E, Dasti A, Segura-Morales C, De Andrés-Aguayo L, Gómez A, Goldmann J, Jaenisch R, Graf T. Tian TV, et al. Among authors: sardina jl. Nat Cell Biol. 2019 Jul;21(7):824-834. doi: 10.1038/s41556-019-0342-1. Epub 2019 Jun 24. Nat Cell Biol. 2019. PMID: 31235934 Free PMC article.
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