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Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering.
Maffioletti SM, Sarcar S, Henderson ABH, Mannhardt I, Pinton L, Moyle LA, Steele-Stallard H, Cappellari O, Wells KE, Ferrari G, Mitchell JS, Tyzack GE, Kotiadis VN, Khedr M, Ragazzi M, Wang W, Duchen MR, Patani R, Zammit PS, Wells DJ, Eschenhagen T, Tedesco FS. Maffioletti SM, et al. Among authors: sarcar s. Cell Rep. 2018 Apr 17;23(3):899-908. doi: 10.1016/j.celrep.2018.03.091. Cell Rep. 2018. PMID: 29669293 Free PMC article.
Next-generation muscle-directed gene therapy by in silico vector design.
Sarcar S, Tulalamba W, Rincon MY, Tipanee J, Pham HQ, Evens H, Boon D, Samara-Kuko E, Keyaerts M, Loperfido M, Berardi E, Jarmin S, In't Veld P, Dickson G, Lahoutte T, Sampaolesi M, De Bleser P, VandenDriessche T, Chuah MK. Sarcar S, et al. Nat Commun. 2019 Jan 30;10(1):492. doi: 10.1038/s41467-018-08283-7. Nat Commun. 2019. PMID: 30700722 Free PMC article.
First-in-human imaging using a MR-compatible e4D ultrasound probe for motion management of radiotherapy.
Bednarz BP, Jupitz S, Lee W, Mills D, Chan H, Fiorillo T, Sabitini J, Shoudy D, Patel A, Mitra J, Sarcar S, Wang B, Shepard A, Matrosic C, Holmes J, Culberson W, Bassetti M, Hill P, McMillan A, Zagzebski J, Smith LS, Foo TK. Bednarz BP, et al. Among authors: sarcar s. Phys Med. 2021 Aug;88:104-110. doi: 10.1016/j.ejmp.2021.06.017. Epub 2021 Jul 1. Phys Med. 2021. PMID: 34218199 Free PMC article.
Efficient In Vivo Liver-Directed Gene Editing Using CRISPR/Cas9.
Singh K, Evens H, Nair N, Rincón MY, Sarcar S, Samara-Kuko E, Chuah MK, VandenDriessche T. Singh K, et al. Among authors: sarcar s. Mol Ther. 2018 May 2;26(5):1241-1254. doi: 10.1016/j.ymthe.2018.02.023. Epub 2018 Mar 6. Mol Ther. 2018. PMID: 29599079 Free PMC article.
Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional Cis-regulatory motifs that enable efficient cardiac gene therapy.
Rincon MY, Sarcar S, Danso-Abeam D, Keyaerts M, Matrai J, Samara-Kuko E, Acosta-Sanchez A, Athanasopoulos T, Dickson G, Lahoutte T, De Bleser P, VandenDriessche T, Chuah MK. Rincon MY, et al. Among authors: sarcar s. Mol Ther. 2015 Jan;23(1):43-52. doi: 10.1038/mt.2014.178. Epub 2014 Sep 8. Mol Ther. 2015. PMID: 25195597 Free PMC article.
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