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Chronic stress and antidepressant treatment alter purine metabolism and beta oxidation within mouse brain and serum.
Hamilton PJ, Chen EY, Tolstikov V, Peña CJ, Picone JA, Shah P, Panagopoulos K, Strat AN, Walker DM, Lorsch ZS, Robinson HL, Mervosh NL, Kiraly DD, Sarangarajan R, Narain NR, Kiebish MA, Nestler EJ. Hamilton PJ, et al. Among authors: sarangarajan r. Sci Rep. 2020 Oct 22;10(1):18134. doi: 10.1038/s41598-020-75114-5. Sci Rep. 2020. PMID: 33093530 Free PMC article.
Metabolomic effects of androgen deprivation therapy treatment for prostate cancer.
Chi JT, Lin PH, Tolstikov V, Oyekunle T, Chen EY, Bussberg V, Greenwood B, Sarangarajan R, Narain NR, Kiebish MA, Freedland SJ. Chi JT, et al. Among authors: sarangarajan r. Cancer Med. 2020 Jun;9(11):3691-3702. doi: 10.1002/cam4.3016. Epub 2020 Mar 31. Cancer Med. 2020. PMID: 32232974 Free PMC article. Clinical Trial.
High levels of ubidecarenone (oxidized CoQ10) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma versus non-tumor cells.
Sun J, Patel CB, Jang T, Merchant M, Chen C, Kazerounian S, Diers AR, Kiebish MA, Vishnudas VK, Gesta S, Sarangarajan R, Narain NR, Nagpal S, Recht L. Sun J, et al. Among authors: sarangarajan r. Sci Rep. 2020 Aug 17;10(1):13899. doi: 10.1038/s41598-020-70969-0. Sci Rep. 2020. PMID: 32807842 Free PMC article.
Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer.
Dadali T, Diers AR, Kazerounian S, Muthuswamy SK, Awate P, Ng R, Mogre S, Spencer C, Krumova K, Rockwell HE, McDaniel J, Chen EY, Gao F, Diedrich KT, Vemulapalli V, Rodrigues LO, Akmaev VR, Thapa K, Hidalgo M, Bose A, Vishnudas VK, Moser AJ, Granger E, Kiebish MA, Gesta S, Narain NR, Sarangarajan R. Dadali T, et al. Among authors: sarangarajan r. Sci Rep. 2021 Mar 11;11(1):5749. doi: 10.1038/s41598-021-84852-z. Sci Rep. 2021. PMID: 33707480 Free PMC article.
Impact of hemolysis on multi-OMIC pancreatic biomarker discovery to derisk biomarker development in precision medicine studies.
Searfoss R, Shah P, Ofori-Mensa K, Bussberg V, Tolstikov V, Greenwood B, Li H, Richardson K, Miller GM, DeCicco C, Granger E, Rodrigues LO, Grund EM, Moser AJ, Sarangarajan R, Narain NR, Kiebish MA. Searfoss R, et al. Among authors: sarangarajan r. Sci Rep. 2022 Jan 24;12(1):1186. doi: 10.1038/s41598-022-05152-8. Sci Rep. 2022. PMID: 35075163 Free PMC article.
Dynamic Assessment of Functional Lipidomic Analysis in Human Urine.
Rockwell HE, Gao F, Chen EY, McDaniel J, Sarangarajan R, Narain NR, Kiebish MA. Rockwell HE, et al. Among authors: sarangarajan r. Lipids. 2016 Jul;51(7):875-86. doi: 10.1007/s11745-016-4142-0. Epub 2016 Apr 1. Lipids. 2016. PMID: 27038173
79 results