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Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.
Amblard F, LeCher JC, De R, Zhou S, Liu P, Goh SL, Tao S, Patel D, Downs-Bowen J, Zandi K, Zhang H, Chaudhry G, McBrayer T, Muczynski M, Al-Homoudi A, Engel J, Lan S, Sarafianos SG, Kovari LC, Schinazi RF. Amblard F, et al. Among authors: sarafianos sg. Eur J Med Chem. 2024 Mar 15;268:116263. doi: 10.1016/j.ejmech.2024.116263. Epub 2024 Feb 24. Eur J Med Chem. 2024. PMID: 38432056
Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro.
Yadav R, Courouble VV, Dey SK, Harrison JJEK, Timm J, Hopkins JB, Slack RL, Sarafianos SG, Ruiz FX, Griffin PR, Arnold E. Yadav R, et al. Among authors: sarafianos sg. Sci Adv. 2022 Dec 9;8(49):eadd2191. doi: 10.1126/sciadv.add2191. Epub 2022 Dec 9. Sci Adv. 2022. PMID: 36490335 Free PMC article.
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS.
Cicka D, Niu Q, Qui M, Qian K, Miller E, Fan D, Mo X, Ivanov AA, Sarafianos SG, Du Y, Fu H. Cicka D, et al. Among authors: sarafianos sg. J Mol Cell Biol. 2023 Aug 3;15(3):mjad017. doi: 10.1093/jmcb/mjad017. J Mol Cell Biol. 2023. PMID: 36921991 Free PMC article.
Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition.
McFadden WM, Casey-Moore MC, Bare GAL, Kirby KA, Wen X, Li G, Wang H, Slack RL, Snyder AA, Lorson ZC, Kaufman IL, Cilento ME, Tedbury PR, Gembicky M, Olson AJ, Torbett BE, Sharpless KB, Sarafianos SG. McFadden WM, et al. Among authors: sarafianos sg. Cell Chem Biol. 2024 Mar 21;31(3):477-486.e7. doi: 10.1016/j.chembiol.2024.02.012. Cell Chem Biol. 2024. PMID: 38518746
Targeting the HIV-1 and HBV Capsids, an EnCore.
McFadden WM, Sarafianos SG. McFadden WM, et al. Among authors: sarafianos sg. Viruses. 2023 Mar 31;15(4):896. doi: 10.3390/v15040896. Viruses. 2023. PMID: 37112877 Free PMC article.
200 results