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Activation of HIV-1 proviruses increases downstream chromatin accessibility.
Shah R, Gallardo CM, Jung YH, Clock B, Dixon JR, McFadden WM, Majumder K, Pintel DJ, Corces VG, Torbett BE, Tedbury PR, Sarafianos SG. Shah R, et al. Among authors: sarafianos sg. iScience. 2022 Nov 8;25(12):105490. doi: 10.1016/j.isci.2022.105490. eCollection 2022 Dec 22. iScience. 2022. PMID: 36505924 Free PMC article.
Targeting the HIV-1 and HBV Capsids, an EnCore.
McFadden WM, Sarafianos SG. McFadden WM, et al. Among authors: sarafianos sg. Viruses. 2023 Mar 31;15(4):896. doi: 10.3390/v15040896. Viruses. 2023. PMID: 37112877 Free PMC article.
The HIV-1 capsid core is an opportunistic nuclear import receptor.
Xue G, Yu HJ, Buffone C, Huang SW, Lee K, Goh SL, Gres AT, Guney MH, Sarafianos SG, Luban J, Diaz-Griffero F, KewalRamani VN. Xue G, et al. Among authors: sarafianos sg. Nat Commun. 2023 Jun 24;14(1):3782. doi: 10.1038/s41467-023-39146-5. Nat Commun. 2023. PMID: 37355754 Free PMC article.
Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition.
McFadden WM, Casey-Moore MC, Bare GAL, Kirby KA, Wen X, Li G, Wang H, Slack RL, Snyder AA, Lorson ZC, Kaufman IL, Cilento ME, Tedbury PR, Gembicky M, Olson AJ, Torbett BE, Sharpless KB, Sarafianos SG. McFadden WM, et al. Among authors: sarafianos sg. Cell Chem Biol. 2024 Mar 21;31(3):477-486.e7. doi: 10.1016/j.chembiol.2024.02.012. Cell Chem Biol. 2024. PMID: 38518746
A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries.
Bruce A, Adebomi V, Czabala P, Palmer J, McFadden WM, Lorson ZC, Slack RL, Bhardwaj G, Sarafianos SG, Raj M. Bruce A, et al. Among authors: sarafianos sg. Angew Chem Int Ed Engl. 2024 Mar 26:e202320045. doi: 10.1002/anie.202320045. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38529717
200 results