Sapp E - Search Results

1

Preconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons.

Sheng R, Zhang TT, Felice VD, Qin T, Qin ZH, Smith CD, Sapp E, Difiglia M, Waeber C. Sheng R, et al. Among authors: sapp e. J Biol Chem. 2014 Jul 25;289(30):20845-57. doi: 10.1074/jbc.M114.578120. J Biol Chem. 2014. PMID: 24928515 Free PMC article.

2

Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation.

Qin ZH, Wang Y, Kikly KK, Sapp E, Kegel KB, Aronin N, DiFiglia M. Qin ZH, et al. Among authors: sapp e. J Biol Chem. 2001 Mar 16;276(11):8079-86. doi: 10.1074/jbc.M007028200. Epub 2000 Dec 1. J Biol Chem. 2001. PMID: 11102441 Free article.

3

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription.

Kegel KB, Meloni AR, Yi Y, Kim YJ, Doyle E, Cuiffo BG, Sapp E, Wang Y, Qin ZH, Chen JD, Nevins JR, Aronin N, DiFiglia M. Kegel KB, et al. Among authors: sapp e. J Biol Chem. 2002 Mar 1;277(9):7466-76. doi: 10.1074/jbc.M103946200. Epub 2001 Dec 5. J Biol Chem. 2002. PMID: 11739372 Free article.

4

Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction.

Qin ZH, Wang Y, Sapp E, Cuiffo B, Wanker E, Hayden MR, Kegel KB, Aronin N, DiFiglia M. Qin ZH, et al. Among authors: sapp e. J Neurosci. 2004 Jan 7;24(1):269-81. doi: 10.1523/JNEUROSCI.1409-03.2004. J Neurosci. 2004. PMID: 14715959 Free PMC article.

5

Huntingtin associates with acidic phospholipids at the plasma membrane.

Kegel KB, Sapp E, Yoder J, Cuiffo B, Sobin L, Kim YJ, Qin ZH, Hayden MR, Aronin N, Scott DL, Isenberg G, Goldmann WH, DiFiglia M. Kegel KB, et al. Among authors: sapp e. J Biol Chem. 2005 Oct 28;280(43):36464-73. doi: 10.1074/jbc.M503672200. Epub 2005 Aug 5. J Biol Chem. 2005. PMID: 16085648 Free article.

6

Lysosomal proteases are involved in generation of N-terminal huntingtin fragments.

Kim YJ, Sapp E, Cuiffo BG, Sobin L, Yoder J, Kegel KB, Qin ZH, Detloff P, Aronin N, DiFiglia M. Kim YJ, et al. Among authors: sapp e. Neurobiol Dis. 2006 May;22(2):346-56. doi: 10.1016/j.nbd.2005.11.012. Epub 2006 Jan 19. Neurobiol Dis. 2006. PMID: 16423528

7

A function of huntingtin in guanine nucleotide exchange on Rab11.

Li X, Sapp E, Valencia A, Kegel KB, Qin ZH, Alexander J, Masso N, Reeves P, Ritch JJ, Zeitlin S, Aronin N, Difiglia M. Li X, et al. Among authors: sapp e. Neuroreport. 2008 Oct 29;19(16):1643-7. doi: 10.1097/WNR.0b013e328315cd4c. Neuroreport. 2008. PMID: 18845944

8

Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease.

Valencia A, Reeves PB, Sapp E, Li X, Alexander J, Kegel KB, Chase K, Aronin N, DiFiglia M. Valencia A, et al. Among authors: sapp e. J Neurosci Res. 2010 Jan;88(1):179-90. doi: 10.1002/jnr.22184. J Neurosci Res. 2010. PMID: 19642201

9

Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo.

Legleiter J, Mitchell E, Lotz GP, Sapp E, Ng C, DiFiglia M, Thompson LM, Muchowski PJ. Legleiter J, et al. Among authors: sapp e. J Biol Chem. 2010 May 7;285(19):14777-90. doi: 10.1074/jbc.M109.093708. Epub 2010 Mar 10. J Biol Chem. 2010. PMID: 20220138 Free PMC article.

10

Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein.

Fox JH, Connor T, Stiles M, Kama J, Lu Z, Dorsey K, Lieberman G, Sapp E, Cherny RA, Banks M, Volitakis I, DiFiglia M, Berezovska O, Bush AI, Hersch SM. Fox JH, et al. Among authors: sapp e. J Biol Chem. 2011 May 20;286(20):18320-30. doi: 10.1074/jbc.M110.199448. Epub 2011 Mar 30. J Biol Chem. 2011. PMID: 21454633 Free PMC article.

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