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MYH10 activation rescues contractile defects in arrhythmogenic cardiomyopathy (ACM).
García-Quintáns N, Sacristán S, Márquez-López C, Sánchez-Ramos C, Martinez-de-Benito F, Siniscalco D, González-Guerra A, Camafeita E, Roche-Molina M, Lytvyn M, Morera D, Guillen MI, Sanguino MA, Sanz-Rosa D, Martín-Pérez D, Garcia R, Bernal JA. García-Quintáns N, et al. Among authors: sanz rosa d. Nat Commun. 2023 Oct 13;14(1):6461. doi: 10.1038/s41467-023-41981-5. Nat Commun. 2023. PMID: 37833253 Free PMC article.
The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis.
Roche-Molina M, Hardwick B, Sanchez-Ramos C, Sanz-Rosa D, Gewert D, Cruz FM, Gonzalez-Guerra A, Andres V, Palma JA, Ibanez B, Mckenzie G, Bernal JA. Roche-Molina M, et al. Among authors: sanz rosa d. Sci Rep. 2020 Jul 15;10(1):11636. doi: 10.1038/s41598-020-68350-2. Sci Rep. 2020. PMID: 32669659 Free PMC article.
Sustained Elevated Blood Pressure Accelerates Atherosclerosis Development in a Preclinical Model of Disease.
Gonzalez-Guerra A, Roche-Molina M, García-Quintáns N, Sánchez-Ramos C, Martín-Pérez D, Lytvyn M, de Nicolás-Hernández J, Rivera-Torres J, Arroyo DF, Sanz-Rosa D, Bernal JA. Gonzalez-Guerra A, et al. Among authors: sanz rosa d. Int J Mol Sci. 2021 Aug 6;22(16):8448. doi: 10.3390/ijms22168448. Int J Mol Sci. 2021. PMID: 34445154 Free PMC article.
β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes.
García-Prieto J, García-Ruiz JM, Sanz-Rosa D, Pun A, García-Alvarez A, Davidson SM, Fernández-Friera L, Nuno-Ayala M, Fernández-Jiménez R, Bernal JA, Izquierdo-Garcia JL, Jimenez-Borreguero J, Pizarro G, Ruiz-Cabello J, Macaya C, Fuster V, Yellon DM, Ibanez B. García-Prieto J, et al. Basic Res Cardiol. 2014 Jul;109(4):422. doi: 10.1007/s00395-014-0422-0. Epub 2014 Jun 21. Basic Res Cardiol. 2014. PMID: 24951958
Neutrophil stunning by metoprolol reduces infarct size.
García-Prieto J, Villena-Gutiérrez R, Gómez M, Bernardo E, Pun-García A, García-Lunar I, Crainiciuc G, Fernández-Jiménez R, Sreeramkumar V, Bourio-Martínez R, García-Ruiz JM, Del Valle AS, Sanz-Rosa D, Pizarro G, Fernández-Ortiz A, Hidalgo A, Fuster V, Ibanez B. García-Prieto J, et al. Nat Commun. 2017 Apr 18;8:14780. doi: 10.1038/ncomms14780. Nat Commun. 2017. PMID: 28416795 Free PMC article.
Mirabegron, a Clinically Approved β3 Adrenergic Receptor Agonist, Does Not Reduce Infarct Size in a Swine Model of Reperfused Myocardial Infarction.
Rossello X, Piñero A, Fernández-Jiménez R, Sánchez-González J, Pizarro G, Galán-Arriola C, Lobo-Gonzalez M, Vilchez JP, García-Prieto J, García-Ruiz JM, García-Álvarez A, Sanz-Rosa D, Ibanez B. Rossello X, et al. J Cardiovasc Transl Res. 2018 Aug;11(4):310-318. doi: 10.1007/s12265-018-9819-8. Epub 2018 Aug 2. J Cardiovasc Transl Res. 2018. PMID: 30073540
The future: therapy of myocardial protection.
Sanz-Rosa D, García-Prieto J, Ibanez B. Sanz-Rosa D, et al. Ann N Y Acad Sci. 2012 Apr;1254:90-98. doi: 10.1111/j.1749-6632.2012.06501.x. Ann N Y Acad Sci. 2012. PMID: 22548574 Review.
Beta-3 adrenergic agonists reduce pulmonary vascular resistance and improve right ventricular performance in a porcine model of chronic pulmonary hypertension.
García-Álvarez A, Pereda D, García-Lunar I, Sanz-Rosa D, Fernández-Jiménez R, García-Prieto J, Nuño-Ayala M, Sierra F, Santiago E, Sandoval E, Campelos P, Agüero J, Pizarro G, Peinado VI, Fernández-Friera L, García-Ruiz JM, Barberá JA, Castellá M, Sabaté M, Fuster V, Ibañez B. García-Álvarez A, et al. Basic Res Cardiol. 2016 Jul;111(4):49. doi: 10.1007/s00395-016-0567-0. Epub 2016 Jun 21. Basic Res Cardiol. 2016. PMID: 27328822 Free PMC article.
63 results