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PGC1α Suppresses Prostate Cancer Cell Invasion through ERRα Transcriptional Control.
Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigué A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardón C, Fernández-Ruiz S, Rodriguez-Hernandez I, Hermanova I, Astobiza I, Cortazar AR, Corres-Mendizabal J, Gomez-Muñoz A, Sanz-Moreno V, Torrano V, Carracedo A. Valcarcel-Jimenez L, et al. Cancer Res. 2019 Dec 15;79(24):6153-6165. doi: 10.1158/0008-5472.CAN-19-1231. Epub 2019 Oct 8. Cancer Res. 2019. PMID: 31594836
Rho, ROCK and actomyosin contractility in metastasis as drug targets.
Rodriguez-Hernandez I, Cantelli G, Bruce F, Sanz-Moreno V. Rodriguez-Hernandez I, et al. F1000Res. 2016 Apr 29;5:F1000 Faculty Rev-783. doi: 10.12688/f1000research.7909.1. eCollection 2016. F1000Res. 2016. PMID: 27158478 Free PMC article. Review.
The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.
Torrano V, Valcarcel-Jimenez L, Cortazar AR, Liu X, Urosevic J, Castillo-Martin M, Fernández-Ruiz S, Morciano G, Caro-Maldonado A, Guiu M, Zúñiga-García P, Graupera M, Bellmunt A, Pandya P, Lorente M, Martín-Martín N, Sutherland JD, Sanchez-Mosquera P, Bozal-Basterra L, Zabala-Letona A, Arruabarrena-Aristorena A, Berenguer A, Embade N, Ugalde-Olano A, Lacasa-Viscasillas I, Loizaga-Iriarte A, Unda-Urzaiz M, Schultz N, Aransay AM, Sanz-Moreno V, Barrio R, Velasco G, Pinton P, Cordon-Cardo C, Locasale JW, Gomis RR, Carracedo A. Torrano V, et al. Nat Cell Biol. 2016 Jun;18(6):645-656. doi: 10.1038/ncb3357. Epub 2016 May 23. Nat Cell Biol. 2016. PMID: 27214280 Free PMC article.
TGFΒ-induced transcription in cancer.
Cantelli G, Crosas-Molist E, Georgouli M, Sanz-Moreno V. Cantelli G, et al. Semin Cancer Biol. 2017 Feb;42:60-69. doi: 10.1016/j.semcancer.2016.08.009. Epub 2016 Aug 30. Semin Cancer Biol. 2017. PMID: 27586372 Free PMC article. Review.
Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling.
Josephs DH, Bax HJ, Dodev T, Georgouli M, Nakamura M, Pellizzari G, Saul L, Karagiannis P, Cheung A, Herraiz C, Ilieva KM, Correa I, Fittall M, Crescioli S, Gazinska P, Woodman N, Mele S, Chiaruttini G, Gilbert AE, Koers A, Bracher M, Selkirk C, Lentfer H, Barton C, Lever E, Muirhead G, Tsoka S, Canevari S, Figini M, Montes A, Downes N, Dombrowicz D, Corrigan CJ, Beavil AJ, Nestle FO, Jones PS, Gould HJ, Sanz-Moreno V, Blower PJ, Spicer JF, Karagiannis SN. Josephs DH, et al. Cancer Res. 2017 Mar 1;77(5):1127-1141. doi: 10.1158/0008-5472.CAN-16-1829. Epub 2017 Jan 17. Cancer Res. 2017. PMID: 28096174 Free PMC article.
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