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Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor.
Fernandez-Lopez L, Cea-Rama I, Alvarez-Malmagro J, Ressmann AK, Gonzalez-Alfonso JL, Coscolín C, Shahgaldian P, Plou FJ, Modregger J, Pita M, Sanz-Aparicio J, Ferrer M. Fernandez-Lopez L, et al. Among authors: sanz aparicio j. Chem Commun (Camb). 2023 Aug 1;59(62):9469-9472. doi: 10.1039/d3cc01946b. Chem Commun (Camb). 2023. PMID: 37376994
Relevance of aromatic and polar amino acids in the specificity of Inulinase ISO3 from Kluyveromyces marxianus: A molecular dynamics approach with an experimental verification.
Trapala J, González-Andrade M, Olvera C, Cayetano-Cruz M, Sanz-Aparicio J, Jimenez-Ortega E, Bustos-Jaimes I, Montiel C. Trapala J, et al. Among authors: sanz aparicio j. Int J Biol Macromol. 2023 Jul 1;242(Pt 1):124734. doi: 10.1016/j.ijbiomac.2023.124734. Epub 2023 May 5. Int J Biol Macromol. 2023. PMID: 37150366
Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids.
Gomez de Santos P, González-Benjumea A, Fernandez-Garcia A, Aranda C, Wu Y, But A, Molina-Espeja P, Maté DM, Gonzalez-Perez D, Zhang W, Kiebist J, Scheibner K, Hofrichter M, Świderek K, Moliner V, Sanz-Aparicio J, Hollmann F, Gutiérrez A, Alcalde M. Gomez de Santos P, et al. Among authors: sanz aparicio j. Angew Chem Int Ed Engl. 2023 Feb 20;62(9):e202217372. doi: 10.1002/anie.202217372. Epub 2023 Jan 24. Angew Chem Int Ed Engl. 2023. PMID: 36583658
The bone-degrading enzyme machinery: From multi-component understanding to the treatment of residues from the meat industry.
Fernandez-Lopez L, Sanchez-Carrillo S, García-Moyano A, Borchert E, Almendral D, Alonso S, Cea-Rama I, Miguez N, Larsen Ø, Werner J, Makarova KS, Plou FJ, Dahlgren TG, Sanz-Aparicio J, Hentschel U, Bjerga GEK, Ferrer M. Fernandez-Lopez L, et al. Among authors: sanz aparicio j. Comput Struct Biotechnol J. 2021 Nov 23;19:6328-6342. doi: 10.1016/j.csbj.2021.11.027. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34938409 Free PMC article.
Structural inspection and protein motions modelling of a fungal glycoside hydrolase family 18 chitinase by crystallography depicts a dynamic enzymatic mechanism.
Jiménez-Ortega E, Kidibule PE, Fernández-Lobato M, Sanz-Aparicio J. Jiménez-Ortega E, et al. Among authors: sanz aparicio j. Comput Struct Biotechnol J. 2021 Oct 2;19:5466-5478. doi: 10.1016/j.csbj.2021.09.027. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34712392 Free PMC article.
87 results