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Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis.
Niemsiri V, Rosenthal SB, Nievergelt CM, Maihofer AX, Marchetto MC, Santos R, Shekhtman T, Alliey-Rodriguez N, Anand A, Balaraman Y, Berrettini WH, Bertram H, Burdick KE, Calabrese JR, Calkin CV, Conroy C, Coryell WH, DeModena A, Eyler LT, Feeder S, Fisher C, Frazier N, Frye MA, Gao K, Garnham J, Gershon ES, Goes FS, Goto T, Harrington GJ, Jakobsen P, Kamali M, Kelly M, Leckband SG, Lohoff FW, McCarthy MJ, McInnis MG, Craig D, Millett CE, Mondimore F, Morken G, Nurnberger JI, Donovan CO, Øedegaard KJ, Ryan K, Schinagle M, Shilling PD, Slaney C, Stapp EK, Stautland A, Tarwater B, Zandi PP, Alda M, Fisch KM, Gage FH, Kelsoe JR. Niemsiri V, et al. Among authors: santos r. Mol Psychiatry. 2024 Jan;29(1):6-19. doi: 10.1038/s41380-022-01909-9. Epub 2023 Mar 29. Mol Psychiatry. 2024. PMID: 36991131 Free PMC article.
Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium.
Stern S, Santos R, Marchetto MC, Mendes APD, Rouleau GA, Biesmans S, Wang QW, Yao J, Charnay P, Bang AG, Alda M, Gage FH. Stern S, et al. Among authors: santos r. Mol Psychiatry. 2018 Jun;23(6):1453-1465. doi: 10.1038/mp.2016.260. Epub 2017 Feb 28. Mol Psychiatry. 2018. PMID: 28242870 Free PMC article.
Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells.
Santos R, Vadodaria KC, Jaeger BN, Mei A, Lefcochilos-Fogelquist S, Mendes APD, Erikson G, Shokhirev M, Randolph-Moore L, Fredlender C, Dave S, Oefner R, Fitzpatrick C, Pena M, Barron JJ, Ku M, Denli AM, Kerman BE, Charnay P, Kelsoe JR, Marchetto MC, Gage FH. Santos R, et al. Stem Cell Reports. 2017 Jun 6;8(6):1757-1769. doi: 10.1016/j.stemcr.2017.05.011. Stem Cell Reports. 2017. PMID: 28591655 Free PMC article.
Mitochondria, Metabolism, and Redox Mechanisms in Psychiatric Disorders.
Kim Y, Vadodaria KC, Lenkei Z, Kato T, Gage FH, Marchetto MC, Santos R. Kim Y, et al. Among authors: santos r. Antioxid Redox Signal. 2019 Aug 1;31(4):275-317. doi: 10.1089/ars.2018.7606. Epub 2019 Feb 1. Antioxid Redox Signal. 2019. PMID: 30585734 Free PMC article. Review.
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells.
Marchetto MC, Hrvoj-Mihic B, Kerman BE, Yu DX, Vadodaria KC, Linker SB, Narvaiza I, Santos R, Denli AM, Mendes AP, Oefner R, Cook J, McHenry L, Grasmick JM, Heard K, Fredlender C, Randolph-Moore L, Kshirsagar R, Xenitopoulos R, Chou G, Hah N, Muotri AR, Padmanabhan K, Semendeferi K, Gage FH. Marchetto MC, et al. Among authors: santos r. Elife. 2019 Feb 7;8:e37527. doi: 10.7554/eLife.37527. Elife. 2019. PMID: 30730291 Free PMC article.
Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder.
Stern S, Sarkar A, Stern T, Mei A, Mendes APD, Stern Y, Goldberg G, Galor D, Nguyen T, Randolph-Moore L, Kim Y, Rouleau G, Bang A, Alda M, Santos R, Marchetto MC, Gage FH. Stern S, et al. Among authors: santos r. Biol Psychiatry. 2020 Jul 15;88(2):139-149. doi: 10.1016/j.biopsych.2019.09.018. Epub 2019 Oct 1. Biol Psychiatry. 2020. PMID: 31732108 Free PMC article.
A Physiological Instability Displayed in Hippocampal Neurons Derived From Lithium-Nonresponsive Bipolar Disorder Patients.
Stern S, Sarkar A, Galor D, Stern T, Mei A, Stern Y, Mendes APD, Randolph-Moore L, Rouleau G, Bang AG, Santos R, Alda M, Marchetto MC, Gage FH. Stern S, et al. Among authors: santos r. Biol Psychiatry. 2020 Jul 15;88(2):150-158. doi: 10.1016/j.biopsych.2020.01.020. Epub 2020 Feb 4. Biol Psychiatry. 2020. PMID: 32278494 Free PMC article.
6,555 results