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The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. Puente BN, et al. Among authors: santos cx. Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032. Cell. 2014. PMID: 24766806 Free PMC article.
Hypoxia induces heart regeneration in adult mice.
Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA. Nakada Y, et al. Among authors: santos cx. Nature. 2017 Jan 12;541(7636):222-227. doi: 10.1038/nature20173. Epub 2016 Oct 31. Nature. 2017. PMID: 27798600
Contractile Function During Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation.
Zhang M, Prosser BL, Bamboye MA, Gondim ANS, Santos CX, Martin D, Ghigo A, Perino A, Brewer AC, Ward CW, Hirsch E, Lederer WJ, Shah AM. Zhang M, et al. Among authors: santos cx. J Am Coll Cardiol. 2015 Jul 21;66(3):261-272. doi: 10.1016/j.jacc.2015.05.020. J Am Coll Cardiol. 2015. PMID: 26184620 Free PMC article.
Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo.
Ray R, Murdoch CE, Wang M, Santos CX, Zhang M, Alom-Ruiz S, Anilkumar N, Ouattara A, Cave AC, Walker SJ, Grieve DJ, Charles RL, Eaton P, Brewer AC, Shah AM. Ray R, et al. Among authors: santos cx. Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1368-76. doi: 10.1161/ATVBAHA.110.219238. Epub 2011 Mar 17. Arterioscler Thromb Vasc Biol. 2011. PMID: 21415386
Response by Prysyazhna et al to Letter Regarding Article, "Blood Pressure-Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase".
Prysyazhna O, Wolhuter K, Switzer C, Santos C, Yang X, Lynham S, Shah AM, Eaton P, Burgoyne JR. Prysyazhna O, et al. Circulation. 2019 Nov 26;140(22):e810-e811. doi: 10.1161/CIRCULATIONAHA.119.043869. Epub 2019 Nov 25. Circulation. 2019. PMID: 31765257 No abstract available.
62 results