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SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer.
Santolla MF, Avino S, Pellegrino M, De Francesco EM, De Marco P, Lappano R, Vivacqua A, Cirillo F, Rigiracciolo DC, Scarpelli A, Abonante S, Maggiolini M. Santolla MF, et al. Cell Death Dis. 2015 Jul 30;6(7):e1834. doi: 10.1038/cddis.2015.201. Cell Death Dis. 2015. PMID: 26225773 Free PMC article.
GPER mediates activation of HIF1α/VEGF signaling by estrogens.
De Francesco EM, Pellegrino M, Santolla MF, Lappano R, Ricchio E, Abonante S, Maggiolini M. De Francesco EM, et al. Among authors: santolla mf. Cancer Res. 2014 Aug 1;74(15):4053-64. doi: 10.1158/0008-5472.CAN-13-3590. Epub 2014 Jun 3. Cancer Res. 2014. PMID: 24894716
Copper activates HIF-1α/GPER/VEGF signalling in cancer cells.
Rigiracciolo DC, Scarpelli A, Lappano R, Pisano A, Santolla MF, De Marco P, Cirillo F, Cappello AR, Dolce V, Belfiore A, Maggiolini M, De Francesco EM. Rigiracciolo DC, et al. Among authors: santolla mf. Oncotarget. 2015 Oct 27;6(33):34158-77. doi: 10.18632/oncotarget.5779. Oncotarget. 2015. PMID: 26415222 Free PMC article.
35 results