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High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition.
Bate-Eya LT, den Hartog IJ, van der Ploeg I, Schild L, Koster J, Santo EE, Westerhout EM, Versteeg R, Caron HN, Molenaar JJ, Dolman ME. Bate-Eya LT, et al. Among authors: santo ee. Oncotarget. 2016 May 10;7(19):27946-58. doi: 10.18632/oncotarget.8547. Oncotarget. 2016. PMID: 27056887 Free PMC article.
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes.
Molenaar JJ, Koster J, Zwijnenburg DA, van Sluis P, Valentijn LJ, van der Ploeg I, Hamdi M, van Nes J, Westerman BA, van Arkel J, Ebus ME, Haneveld F, Lakeman A, Schild L, Molenaar P, Stroeken P, van Noesel MM, Ora I, Santo EE, Caron HN, Westerhout EM, Versteeg R. Molenaar JJ, et al. Among authors: santo ee. Nature. 2012 Feb 22;483(7391):589-93. doi: 10.1038/nature10910. Nature. 2012. PMID: 22367537 Free article.
FOXO protects against age-progressive axonal degeneration.
Hwang I, Oh H, Santo E, Kim DY, Chen JW, Bronson RT, Locasale JW, Na Y, Lee J, Reed S, Toth M, Yu WH, Muller FL, Paik J. Hwang I, et al. Aging Cell. 2018 Feb;17(1):e12701. doi: 10.1111/acel.12701. Epub 2017 Nov 26. Aging Cell. 2018. PMID: 29178390 Free PMC article.
Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma.
Santo EE, Ebus ME, Koster J, Schulte JH, Lakeman A, van Sluis P, Vermeulen J, Gisselsson D, Øra I, Lindner S, Buckley PG, Stallings RL, Vandesompele J, Eggert A, Caron HN, Versteeg R, Molenaar JJ. Santo EE, et al. Oncogene. 2012 Mar 22;31(12):1571-81. doi: 10.1038/onc.2011.344. Epub 2011 Aug 22. Oncogene. 2012. PMID: 21860421
15 results