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Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria.
Alnabulsi S, Santina E, Russo I, Hussein B, Kadirvel M, Chadwick A, Bichenkova EV, Bryce RA, Nolan K, Demonacos C, Stratford IJ, Freeman S. Alnabulsi S, et al. Among authors: santina e. Eur J Med Chem. 2016 Mar 23;111:33-45. doi: 10.1016/j.ejmech.2016.01.022. Epub 2016 Jan 21. Eur J Med Chem. 2016. PMID: 26854376
Evaluating very high energy electron RBE from nanodosimetric pBR322 plasmid DNA damage.
Small KL, Henthorn NT, Angal-Kalinin D, Chadwick AL, Santina E, Aitkenhead A, Kirkby KJ, Smith RJ, Surman M, Jones J, Farabolini W, Corsini R, Gamba D, Gilardi A, Merchant MJ, Jones RM. Small KL, et al. Among authors: santina e. Sci Rep. 2021 Feb 8;11(1):3341. doi: 10.1038/s41598-021-82772-6. Sci Rep. 2021. PMID: 33558553 Free PMC article.
The suitability of micronuclei as markers of relative biological effect.
Heaven CJ, Wanstall HC, Henthorn NT, Warmenhoven JW, Ingram SP, Chadwick AL, Santina E, Honeychurch J, Schmidt CK, Kirkby KJ, Kirkby NF, Burnet NG, Merchant MJ. Heaven CJ, et al. Among authors: santina e. Mutagenesis. 2022 Apr 2;37(1):3-12. doi: 10.1093/mutage/geac001. Mutagenesis. 2022. PMID: 35137176 Free PMC article.
Quantification of damage to plasmid DNA from 35 MeV electrons, 228 MeV protons and 300 kVp X-rays in varying hydroxyl radical scavenging environments.
Wanstall HC, Henthorn NT, Jones J, Santina E, Chadwick AL, Angal-Kalinin D, Morris G, Warmenhoven JW, Smith R, Mathisen S, Merchant MJ, Jones RM. Wanstall HC, et al. Among authors: santina e. J Radiat Res. 2023 May 6;64(3):547-57. doi: 10.1093/jrr/rrad032. Online ahead of print. J Radiat Res. 2023. PMID: 37154587 Free PMC article.
Evaluation of analogues of furan-amidines as inhibitors of NQO2.
Alnabulsi S, Hussein B, Santina E, Alsalahat I, Kadirvel M, Magwaza RN, Bryce RA, Schwalbe CH, Baldwin AG, Russo I, Stratford IJ, Freeman S. Alnabulsi S, et al. Among authors: santina e. Bioorg Med Chem Lett. 2018 May 1;28(8):1292-1297. doi: 10.1016/j.bmcl.2018.03.025. Epub 2018 Mar 12. Bioorg Med Chem Lett. 2018. PMID: 29567345
First in vitro measurement of VHEE relative biological effectiveness (RBE) in lung and prostate cancer cells using the ARES linac at DESY.
Wanstall HC, Burkart F, Dinter H, Kellermeier M, Kuropka W, Mayet F, Vinatier T, Santina E, Chadwick AL, Merchant MJ, Henthorn NT, Köpke M, Stacey B, Jaster-Merz S, Jones RM. Wanstall HC, et al. Among authors: santina e. Sci Rep. 2024 May 13;14(1):10957. doi: 10.1038/s41598-024-60585-7. Sci Rep. 2024. PMID: 38740830 Free PMC article.