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In vitro evaluation of antileishmanial activity, mode of action and cellular response induced by vanillin synthetic derivatives against Leishmania species able to cause cutaneous and visceral leishmaniasis.
Freitas CS, Santiago SS, Lage DP, Antinarelli LMR, Oliveira FM, Vale DL, Martins VT, Magalhaes LND, Bandeira RS, Ramos FF, Pereira IAG, de Jesus MM, Ludolf F, Tavares GSV, Costa AV, Ferreira RS, Coimbra ES, Teixeira RR, Coelho EAF. Freitas CS, et al. Among authors: santiago ss. Exp Parasitol. 2023 Aug;251:108555. doi: 10.1016/j.exppara.2023.108555. Epub 2023 May 27. Exp Parasitol. 2023. PMID: 37247802
New synthetic molecules incorporated into polymeric micelles used for treatment against visceral leishmaniasis.
Freitas CS, Pereira IAG, Lage DP, Vale DL, Pimenta BL, Soares NP, Santiago SS, Martins VT, Câmara RSB, Jesus MM, Tavares GSV, Ramos FF, Ludolf F, Magalhães LND, Oliveira FM, Duarte MC, Chávez-Fumagalli MA, Costa AV, Roatt BM, Teixeira RR, Coelho EAF. Freitas CS, et al. Among authors: santiago ss. Cytokine. 2024 May;177:156543. doi: 10.1016/j.cyto.2024.156543. Epub 2024 Feb 18. Cytokine. 2024. PMID: 38373365
Treatment using vanillin-derived synthetic molecules incorporated into polymeric micelles is effective against infection caused by Leishmania amazonensis species.
Pereira IAG, Freitas CS, Câmara RSB, Jesus MM, Lage DP, Tavares GSV, Soyer TG, Ramos FF, Soares NP, Santiago SS, Martins VT, Vale DL, Pimenta BL, Ludolf F, Oliveira FM, Duarte MC, Chávez-Fumagalli MA, Costa AV, Gonçalves DU, Roatt BM, Teixeira RR, Coelho EAF. Pereira IAG, et al. Among authors: santiago ss. Exp Parasitol. 2024 Mar 19;260:108743. doi: 10.1016/j.exppara.2024.108743. Online ahead of print. Exp Parasitol. 2024. PMID: 38513973