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An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M. Zhong Q, et al. Among authors: santhanam b. Mol Syst Biol. 2016 Apr 22;12(4):865. doi: 10.15252/msb.20156484. Mol Syst Biol. 2016. PMID: 27107014 Free PMC article.
Proto-genes and de novo gene birth.
Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME, Vidal M. Carvunis AR, et al. Among authors: santhanam b. Nature. 2012 Jul 19;487(7407):370-4. doi: 10.1038/nature11184. Nature. 2012. PMID: 22722833 Free PMC article.
Viral perturbations of host networks reflect disease etiology.
Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A, Zhao B, Santhanam B, Braun P, Simonis N, Huh KW, Hellner K, Grace M, Chen A, Rubio R, Marto JA, Christakis NA, Kieff E, Roth FP, Roecklein-Canfield J, Decaprio JA, Cusick ME, Quackenbush J, Hill DE, Münger K, Vidal M, Barabási AL. Gulbahce N, et al. Among authors: santhanam b. PLoS Comput Biol. 2012;8(6):e1002531. doi: 10.1371/journal.pcbi.1002531. Epub 2012 Jun 28. PLoS Comput Biol. 2012. PMID: 22761553 Free PMC article.
Independently evolved virulence effectors converge onto hubs in a plant immune system network.
Mukhtar MS, Carvunis AR, Dreze M, Epple P, Steinbrenner J, Moore J, Tasan M, Galli M, Hao T, Nishimura MT, Pevzner SJ, Donovan SE, Ghamsari L, Santhanam B, Romero V, Poulin MM, Gebreab F, Gutierrez BJ, Tam S, Monachello D, Boxem M, Harbort CJ, McDonald N, Gai L, Chen H, He Y; European Union Effectoromics Consortium; Vandenhaute J, Roth FP, Hill DE, Ecker JR, Vidal M, Beynon J, Braun P, Dangl JL. Mukhtar MS, et al. Among authors: santhanam b. Science. 2011 Jul 29;333(6042):596-601. doi: 10.1126/science.1203659. Science. 2011. PMID: 21798943 Free PMC article.
Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Anandapadamanaban M, Masson GR, Perisic O, Berndt A, Kaufman J, Johnson CM, Santhanam B, Rogala KB, Sabatini DM, Williams RL. Anandapadamanaban M, et al. Among authors: santhanam b. Science. 2019 Oct 11;366(6462):203-210. doi: 10.1126/science.aax3939. Science. 2019. PMID: 31601764 Free PMC article.
Architecture of eukaryotic mRNA 3'-end processing machinery.
Casañal A, Kumar A, Hill CH, Easter AD, Emsley P, Degliesposti G, Gordiyenko Y, Santhanam B, Wolf J, Wiederhold K, Dornan GL, Skehel M, Robinson CV, Passmore LA. Casañal A, et al. Among authors: santhanam b. Science. 2017 Nov 24;358(6366):1056-1059. doi: 10.1126/science.aao6535. Epub 2017 Oct 26. Science. 2017. PMID: 29074584 Free PMC article.
45 results