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Dopamine D4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction.
Rivera A, Gago B, Suárez-Boomgaard D, Yoshitake T, Roales-Buján R, Valderrama-Carvajal A, Bilbao A, Medina-Luque J, Díaz-Cabiale Z, Craenenbroeck KV, Borroto-Escuela DO, Kehr J, Rodríguez de Fonseca F, Santín L, de la Calle A, Fuxe K. Rivera A, et al. Among authors: santin l. Addict Biol. 2017 Sep;22(5):1232-1245. doi: 10.1111/adb.12407. Epub 2016 May 22. Addict Biol. 2017. PMID: 27212105
Fear extinction and acute stress reactivity reveal a role of LPA(1) receptor in regulating emotional-like behaviors.
Pedraza C, Sánchez-López J, Castilla-Ortega E, Rosell-Valle C, Zambrana-Infantes E, García-Fernández M, Rodriguez de Fonseca F, Chun J, Santín LJ, Estivill-Torrús G. Pedraza C, et al. Among authors: santin lj. Brain Struct Funct. 2014 Sep;219(5):1659-72. doi: 10.1007/s00429-013-0592-9. Epub 2013 Jun 18. Brain Struct Funct. 2014. PMID: 23775489
Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex.
García-Díaz B, Riquelme R, Varela-Nieto I, Jiménez AJ, de Diego I, Gómez-Conde AI, Matas-Rico E, Aguirre JÁ, Chun J, Pedraza C, Santín LJ, Fernández O, Rodríguez de Fonseca F, Estivill-Torrús G. García-Díaz B, et al. Brain Struct Funct. 2015 Nov;220(6):3701-20. doi: 10.1007/s00429-014-0885-7. Epub 2014 Sep 17. Brain Struct Funct. 2015. PMID: 25226845
Both genetic deletion and pharmacological blockade of lysophosphatidic acid LPA1 receptor results in increased alcohol consumption.
Castilla-Ortega E, Pavón FJ, Sánchez-Marín L, Estivill-Torrús G, Pedraza C, Blanco E, Suárez J, Santín L, Rodríguez de Fonseca F, Serrano A. Castilla-Ortega E, et al. Among authors: santin l. Neuropharmacology. 2016 Apr;103:92-103. doi: 10.1016/j.neuropharm.2015.12.010. Epub 2015 Dec 15. Neuropharmacology. 2016. PMID: 26700247
121 results