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355 results

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Page 1
MmCMS: mouse models' consensus molecular subtypes of colorectal cancer.
Amirkhah R, Gilroy K, Malla SB, Lannagan TRM, Byrne RM, Fisher NC, Corry SM, Mohamed NE, Naderi-Meshkin H, Mills ML, Campbell AD, Ridgway RA, Ahmaderaghi B, Murray R, Llergo AB, Sanz-Pamplona R, Villanueva A, Batlle E, Salazar R, Lawler M, Sansom OJ, Dunne PD. Amirkhah R, et al. Among authors: sansom oj. Br J Cancer. 2023 Mar;128(7):1333-1343. doi: 10.1038/s41416-023-02157-6. Epub 2023 Jan 30. Br J Cancer. 2023. PMID: 36717674 Free PMC article.
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Gil Vazquez E, Nasreddin N, Valbuena GN, Mulholland EJ, Belnoue-Davis HL, Eggington HR, Schenck RO, Wouters VM, Wirapati P, Gilroy K, Lannagan TRM, Flanagan DJ, Najumudeen AK, Omwenga S, McCorry AMB, Easton A, Koelzer VH, East JE, Morton D, Trusolino L, Maughan T, Campbell AD, Loughrey MB, Dunne PD, Tsantoulis P, Huels DJ, Tejpar S, Sansom OJ, Leedham SJ. Gil Vazquez E, et al. Among authors: sansom oj. Cell Stem Cell. 2022 Nov 3;29(11):1612. doi: 10.1016/j.stem.2022.09.005. Cell Stem Cell. 2022. PMID: 36332574 Free PMC article. No abstract available.
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors.
Pennel KAF, Hatthakarnkul P, Wood CS, Lian GY, Al-Badran SSF, Quinn JA, Legrini A, Inthagard J, Alexander PG, van Wyk H, Kurniawan A, Hashmi U, Gillespie MA, Mills M, Ammar A, Hay J, Andersen D, Nixon C, Rebus S, Chang DK, Kelly C, Harkin A, Graham J, Church D, Tomlinson I, Saunders M, Iveson T, Lannagan TRM, Jackstadt R, Maka N, Horgan PG, Roxburgh CSD, Sansom OJ, McMillan DC, Steele CW, Jamieson NB, Park JH, Roseweir AK, Edwards J. Pennel KAF, et al. Among authors: sansom oj. J Exp Clin Cancer Res. 2024 Mar 1;43(1):64. doi: 10.1186/s13046-024-02958-4. J Exp Clin Cancer Res. 2024. PMID: 38424636 Free PMC article.
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.
Wagner SJ, Reisenbüchler D, West NP, Niehues JM, Zhu J, Foersch S, Veldhuizen GP, Quirke P, Grabsch HI, van den Brandt PA, Hutchins GGA, Richman SD, Yuan T, Langer R, Jenniskens JCA, Offermans K, Mueller W, Gray R, Gruber SB, Greenson JK, Rennert G, Bonner JD, Schmolze D, Jonnagaddala J, Hawkins NJ, Ward RL, Morton D, Seymour M, Magill L, Nowak M, Hay J, Koelzer VH, Church DN; TransSCOT consortium; Matek C, Geppert C, Peng C, Zhi C, Ouyang X, James JA, Loughrey MB, Salto-Tellez M, Brenner H, Hoffmeister M, Truhn D, Schnabel JA, Boxberg M, Peng T, Kather JN. Wagner SJ, et al. Cancer Cell. 2023 Sep 11;41(9):1650-1661.e4. doi: 10.1016/j.ccell.2023.08.002. Epub 2023 Aug 30. Cancer Cell. 2023. PMID: 37652006 Free PMC article.
Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition.
Holt AK, Najumudeen AK, Collard TJ, Li H, Millett LM, Hoskin AJ, Legge DN, Mortensson EMH, Flanagan DJ, Jones N, Kollareddy M, Timms P, Hitchings MD, Cronin J, Sansom OJ, Williams AC, Vincent EE. Holt AK, et al. Among authors: sansom oj. Cancer Metab. 2023 Oct 19;11(1):18. doi: 10.1186/s40170-023-00318-y. Cancer Metab. 2023. PMID: 37858256 Free PMC article.
Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II-III colorectal cancer from the SCOT and QUASAR 2 trials: a retrospective analysis.
Frei AL, McGuigan A, Sinha RRAK, Jabbar F, Gneo L, Tomasevic T, Harkin A, Iveson T, Saunders MP, Oien KA, Maka N, Pezzella F, Campo L, Browne M, Glaire M, Kildal W, Danielsen HE, Hay J, Edwards J, Sansom O, Kelly C, Tomlinson I, Kerr R, Kerr D, Domingo E; TransSCOT consortium; Church DN, Koelzer VH. Frei AL, et al. Lancet Oncol. 2024 Feb;25(2):198-211. doi: 10.1016/S1470-2045(23)00560-0. Lancet Oncol. 2024. PMID: 38301689 Free article.
Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies.
Domingo E, Kelly C, Hay J, Sansom O, Maka N, Oien K, Iveson T, Saunders M, Kerr R, Tomlinson I, Edwards J, Harkin A, Nowak M, Koelzer V, Easton A, Boukovinas I, Moustou E, Messaritakis I, Chondrozoumaki M, Karagianni M, Pagès F, Arnoux F, Lautard C, Lovera Y, Boquet I, Catteau A, Galon J; TransSCOT Consortium; Souglakos I, Church DN. Domingo E, et al. J Clin Oncol. 2024 Mar 14:JCO2301648. doi: 10.1200/JCO.23.01648. Online ahead of print. J Clin Oncol. 2024. PMID: 38484206
Caffeine Limits Expansion of Apc-Deficient Clones in the Intestine by NOTUM Inhibition.
van Driel MS, Linssen JDG, Flanagan DJ, Vlahov N, Nijman LE, de Groot NE, Elbers CC, Koster J, Sansom OJ, Vermeulen L, van Neerven SM. van Driel MS, et al. Among authors: sansom oj. Cell Mol Gastroenterol Hepatol. 2023;16(4):652-655. doi: 10.1016/j.jcmgh.2023.06.008. Epub 2023 Jun 24. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37364735 Free PMC article. No abstract available.
Co-inhibition of TGF-β and PD-L1 pathways in a metastatic colorectal cancer mouse model triggers interferon responses, innate cells and T cells, alongside metabolic changes and tumor resistance.
Nair R, Lannagan TRM, Jackstadt R, Andrusaite A, Cole J, Boyne C, Nibbs RJB, Sansom OJ, Milling S. Nair R, et al. Among authors: sansom oj. Oncoimmunology. 2024 Mar 20;13(1):2330194. doi: 10.1080/2162402X.2024.2330194. eCollection 2024. Oncoimmunology. 2024. PMID: 38516270 Free PMC article.
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging.
Malviya G, Lannagan TRM, Johnson E, Mackintosh A, Bielik R, Peters A, Soloviev D, Brown G, Jackstadt R, Nixon C, Gilroy K, Campbell A, Sansom OJ, Lewis DY. Malviya G, et al. Among authors: sansom oj. Clin Cancer Res. 2024 Apr 15;30(8):1518-1529. doi: 10.1158/1078-0432.CCR-23-1063. Clin Cancer Res. 2024. PMID: 38493804 Free PMC article.
355 results