Sanguinetti MC - Search Results

1

Marine algal toxin azaspiracid is an open-state blocker of hERG potassium channels.

Twiner MJ, Doucette GJ, Rasky A, Huang XP, Roth BL, Sanguinetti MC. Twiner MJ, et al. Among authors: sanguinetti mc. Chem Res Toxicol. 2012 Sep 17;25(9):1975-84. doi: 10.1021/tx300283t. Epub 2012 Aug 10. Chem Res Toxicol. 2012. PMID: 22856456 Free PMC article.

2

hERG potassium channels and cardiac arrhythmia.

Sanguinetti MC, Tristani-Firouzi M. Sanguinetti MC, et al. Nature. 2006 Mar 23;440(7083):463-9. doi: 10.1038/nature04710. Nature. 2006. PMID: 16554806 Review.

3

Open channel block of HERG K(+) channels by vesnarinone.

Kamiya K, Mitcheson JS, Yasui K, Kodama I, Sanguinetti MC. Kamiya K, et al. Among authors: sanguinetti mc. Mol Pharmacol. 2001 Aug;60(2):244-53. doi: 10.1124/mol.60.2.244. Mol Pharmacol. 2001. PMID: 11455010

4

Single HERG delayed rectifier K+ channels expressed in Xenopus oocytes.

Zou A, Curran ME, Keating MT, Sanguinetti MC. Zou A, et al. Among authors: sanguinetti mc. Am J Physiol. 1997 Mar;272(3 Pt 2):H1309-14. doi: 10.1152/ajpheart.1997.272.3.H1309. Am J Physiol. 1997. PMID: 9087606

5

Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.

Sanguinetti MC, Xu QP. Sanguinetti MC, et al. J Physiol. 1999 Feb 1;514 ( Pt 3)(Pt 3):667-75. doi: 10.1111/j.1469-7793.1999.667ad.x. J Physiol. 1999. PMID: 9882738 Free PMC article.

6

Trapping of a methanesulfonanilide by closure of the HERG potassium channel activation gate.

Mitcheson JS, Chen J, Sanguinetti MC. Mitcheson JS, et al. Among authors: sanguinetti mc. J Gen Physiol. 2000 Mar;115(3):229-40. doi: 10.1085/jgp.115.3.229. J Gen Physiol. 2000. PMID: 10694252 Free PMC article.

7

Revealing the structural basis of action of hERG potassium channel activators and blockers.

Perry M, Sanguinetti M, Mitcheson J. Perry M, et al. J Physiol. 2010 Sep 1;588(Pt 17):3157-67. doi: 10.1113/jphysiol.2010.194670. Epub 2010 Jul 19. J Physiol. 2010. PMID: 20643767 Free PMC article. Review.

8

Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.

Chen J, Seebohm G, Sanguinetti MC. Chen J, et al. Among authors: sanguinetti mc. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12461-6. doi: 10.1073/pnas.192367299. Epub 2002 Sep 3. Proc Natl Acad Sci U S A. 2002. PMID: 12209010 Free PMC article.

9

Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channels.

Suzuki T, Hansen A, Sanguinetti MC. Suzuki T, et al. Among authors: sanguinetti mc. Biochim Biophys Acta. 2016 Apr;1858(4):783-92. doi: 10.1016/j.bbamem.2015.12.024. Epub 2015 Dec 23. Biochim Biophys Acta. 2016. PMID: 26724206 Free PMC article.

10

Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels.

Wu W, Gardner A, Sachse FB, Sanguinetti MC. Wu W, et al. Among authors: sanguinetti mc. Mol Pharmacol. 2016 Oct;90(4):469-82. doi: 10.1124/mol.116.104091. Epub 2016 Aug 8. Mol Pharmacol. 2016. PMID: 27502018 Free PMC article.

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