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Discovery and Characterization of 2-Nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)- N-(pyridin-4-ylmethyl)anilines as Novel Inhibitors of the Aedes aegypti Kir1 ( AeKir1) Channel.
Aretz CD, Morwitzer MJ, Sanford AG, Hogan AM, Portillo MV, Kharade SV, Kramer M, McCarthey JB, Trigueros RR, Piermarini PM, Denton JS, Hopkins CR. Aretz CD, et al. Among authors: sanford ag. ACS Infect Dis. 2019 Jun 14;5(6):917-931. doi: 10.1021/acsinfecdis.8b00368. Epub 2019 Mar 15. ACS Infect Dis. 2019. PMID: 30832472 Free PMC article.
Diaryl Ureas as an Antiprotozoal Chemotype.
Leas DA, Sanford AG, Wu J, Cal M, Kaiser M, Wittlin S, Hemsley RM, Darner EB, Lui LM, Davis PH, Vennerstrom JL. Leas DA, et al. Among authors: sanford ag. ACS Infect Dis. 2021 Jun 11;7(6):1578-1583. doi: 10.1021/acsinfecdis.1c00135. Epub 2021 May 10. ACS Infect Dis. 2021. PMID: 33971090 Free PMC article.
A new chemotype with promise against Trypanosoma cruzi.
Wang X, Cal M, Kaiser M, Buckner FS, Lepesheva GI, Sanford AG, Wallick AI, Davis PH, Vennerstrom JL. Wang X, et al. Among authors: sanford ag. Bioorg Med Chem Lett. 2020 Jan 1;30(1):126778. doi: 10.1016/j.bmcl.2019.126778. Epub 2019 Oct 31. Bioorg Med Chem Lett. 2020. PMID: 31706668 Free PMC article.
Progress in antischistosomal N,N'-diaryl urea SAR.
Wu J, Wang C, Leas D, Vargas M, White KL, Shackleford DM, Chen G, Sanford AG, Hemsley RM, Davis PH, Dong Y, Charman SA, Keiser J, Vennerstrom JL. Wu J, et al. Among authors: sanford ag. Bioorg Med Chem Lett. 2018 Feb 1;28(3):244-248. doi: 10.1016/j.bmcl.2017.12.064. Epub 2017 Dec 29. Bioorg Med Chem Lett. 2018. PMID: 29317164 Free PMC article.
Novel Toxoplasma gondii inhibitor chemotypes.
Sanford AG, Schulze TT, Potluri LP, Hemsley RM, Larson JJ, Judge AK, Zach SJ, Wang X, Charman SA, Vennerstrom JL, Davis PH. Sanford AG, et al. Parasitol Int. 2018 Apr;67(2):107-111. doi: 10.1016/j.parint.2017.10.010. Epub 2018 Jan 4. Parasitol Int. 2018. PMID: 29081387 Free PMC article.
Derivatives of a benzoquinone acyl hydrazone with activity against Toxoplasma gondii.
Sanford AG, Schulze TT, Potluri LP, Watson GF, Darner EB, Zach SJ, Hemsley RM, Wallick AI, Warner RC, Charman SA, Wang X, Vennerstrom JL, Davis PH. Sanford AG, et al. Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):488-492. doi: 10.1016/j.ijpddr.2018.11.001. Epub 2018 Nov 10. Int J Parasitol Drugs Drug Resist. 2018. PMID: 30500526 Free PMC article.