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Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord.
Lee YS, Muthu D, Hall SM, Ramos-Colon C, Rankin D, Hu J, Sandweiss AJ, De Felice M, Xie JY, Vanderah TW, Porreca F, Lai J, Hruby VJ. Lee YS, et al. Among authors: sandweiss aj. J Am Chem Soc. 2014 May 7;136(18):6608-16. doi: 10.1021/ja501677q. Epub 2014 Apr 29. J Am Chem Soc. 2014. PMID: 24742335 Free PMC article.
Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor.
Ramos-Colon CN, Lee YS, Remesic M, Hall SM, LaVigne J, Davis P, Sandweiss AJ, McIntosh MI, Hanson J, Largent-Milnes TM, Vanderah TW, Streicher J, Porreca F, Hruby VJ. Ramos-Colon CN, et al. Among authors: sandweiss aj. J Med Chem. 2016 Nov 23;59(22):10291-10298. doi: 10.1021/acs.jmedchem.6b01411. Epub 2016 Nov 8. J Med Chem. 2016. PMID: 27797517 Free PMC article.
Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury.
Bruhns RP, Sulaiman MI, Gaub M, Bae EH, Davidson Knapp RB, Larson AR, Smith A, Coleman DL, Staatz WD, Sandweiss AJ, Joseph B, Hay M, Largent-Milnes TM, Vanderah TW. Bruhns RP, et al. Among authors: sandweiss aj. Front Behav Neurosci. 2022 Aug 4;16:903980. doi: 10.3389/fnbeh.2022.903980. eCollection 2022. Front Behav Neurosci. 2022. PMID: 35990729 Free PMC article.
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