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The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.
Yang Y, MacLeod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G, Sasisekharan R, Naggi A, Torri G, Casu B, Vlodavsky I, Suva LJ, Epstein J, Yaccoby S, Shaughnessy JD Jr, Barlogie B, Sanderson RD. Yang Y, et al. Among authors: sanderson rd. Blood. 2007 Sep 15;110(6):2041-8. doi: 10.1182/blood-2007-04-082495. Epub 2007 May 29. Blood. 2007. PMID: 17536013 Free PMC article.
Heparan sulfate chains of syndecan-1 regulate ectodomain shedding.
Ramani VC, Pruett PS, Thompson CA, DeLucas LD, Sanderson RD. Ramani VC, et al. Among authors: sanderson rd. J Biol Chem. 2012 Mar 23;287(13):9952-9961. doi: 10.1074/jbc.M111.330803. Epub 2012 Feb 1. J Biol Chem. 2012. PMID: 22298773 Free PMC article.
The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.
Ramani VC, Purushothaman A, Stewart MD, Thompson CA, Vlodavsky I, Au JL, Sanderson RD. Ramani VC, et al. Among authors: sanderson rd. FEBS J. 2013 May;280(10):2294-306. doi: 10.1111/febs.12168. Epub 2013 Mar 4. FEBS J. 2013. PMID: 23374281 Free PMC article. Review.
134 results