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Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality.
Ntini E, Järvelin AI, Bornholdt J, Chen Y, Boyd M, Jørgensen M, Andersson R, Hoof I, Schein A, Andersen PR, Andersen PK, Preker P, Valen E, Zhao X, Pelechano V, Steinmetz LM, Sandelin A, Jensen TH. Ntini E, et al. Among authors: sandelin a. Nat Struct Mol Biol. 2013 Aug;20(8):923-8. doi: 10.1038/nsmb.2640. Epub 2013 Jul 14. Nat Struct Mol Biol. 2013. PMID: 23851456
An atlas of active enhancers across human cell types and tissues.
Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, Bornholdt J, Boyd M, Chen Y, Zhao X, Schmidl C, Suzuki T, Ntini E, Arner E, Valen E, Li K, Schwarzfischer L, Glatz D, Raithel J, Lilje B, Rapin N, Bagger FO, Jørgensen M, Andersen PR, Bertin N, Rackham O, Burroughs AM, Baillie JK, Ishizu Y, Shimizu Y, Furuhata E, Maeda S, Negishi Y, Mungall CJ, Meehan TF, Lassmann T, Itoh M, Kawaji H, Kondo N, Kawai J, Lennartsson A, Daub CO, Heutink P, Hume DA, Jensen TH, Suzuki H, Hayashizaki Y, Müller F, Forrest ARR, Carninci P, Rehli M, Sandelin A. Andersson R, et al. Among authors: sandelin a. Nature. 2014 Mar 27;507(7493):455-461. doi: 10.1038/nature12787. Nature. 2014. PMID: 24670763 Free PMC article.
Human Gene Promoters Are Intrinsically Bidirectional.
Andersson R, Chen Y, Core L, Lis JT, Sandelin A, Jensen TH. Andersson R, et al. Among authors: sandelin a. Mol Cell. 2015 Nov 5;60(3):346-7. doi: 10.1016/j.molcel.2015.10.015. Mol Cell. 2015. PMID: 26545074 Free PMC article. No abstract available.
Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
Meola N, Domanski M, Karadoulama E, Chen Y, Gentil C, Pultz D, Vitting-Seerup K, Lykke-Andersen S, Andersen JS, Sandelin A, Jensen TH. Meola N, et al. Among authors: sandelin a. Mol Cell. 2016 Nov 3;64(3):520-533. doi: 10.1016/j.molcel.2016.09.025. Epub 2016 Oct 27. Mol Cell. 2016. PMID: 27871484 Free article.
161 results