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Advanced preclinical models for evaluation of drug-induced liver injury - consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET].
Fernandez-Checa JC, Bagnaninchi P, Ye H, Sancho-Bru P, Falcon-Perez JM, Royo F, Garcia-Ruiz C, Konu O, Miranda J, Lunov O, Dejneka A, Elfick A, McDonald A, Sullivan GJ, Aithal GP, Lucena MI, Andrade RJ, Fromenty B, Kranendonk M, Cubero FJ, Nelson LJ. Fernandez-Checa JC, et al. J Hepatol. 2021 Oct;75(4):935-959. doi: 10.1016/j.jhep.2021.06.021. Epub 2021 Jun 24. J Hepatol. 2021. PMID: 34171436 Free article. Review.
Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans.
Moreno M, Chaves JF, Sancho-Bru P, Ramalho F, Ramalho LN, Mansego ML, Ivorra C, Dominguez M, Conde L, Millán C, Marí M, Colmenero J, Lozano JJ, Jares P, Vidal J, Forns X, Arroyo V, Caballería J, Ginès P, Bataller R. Moreno M, et al. Hepatology. 2010 Mar;51(3):974-85. doi: 10.1002/hep.23421. Hepatology. 2010. PMID: 20077562 Free article.
CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis.
Affò S, Morales-Ibanez O, Rodrigo-Torres D, Altamirano J, Blaya D, Dapito DH, Millán C, Coll M, Caviglia JM, Arroyo V, Caballería J, Schwabe RF, Ginès P, Bataller R, Sancho-Bru P. Affò S, et al. Gut. 2014 Nov;63(11):1782-92. doi: 10.1136/gutjnl-2013-306098. Epub 2014 Jan 10. Gut. 2014. PMID: 24415562 Free PMC article.
The biliary epithelium gives rise to liver progenitor cells.
Rodrigo-Torres D, Affò S, Coll M, Morales-Ibanez O, Millán C, Blaya D, Alvarez-Guaita A, Rentero C, Lozano JJ, Maestro MA, Solar M, Arroyo V, Caballería J, van Grunsven LA, Enrich C, Ginès P, Bataller R, Sancho-Bru P. Rodrigo-Torres D, et al. Hepatology. 2014 Oct;60(4):1367-77. doi: 10.1002/hep.27078. Epub 2014 Aug 21. Hepatology. 2014. PMID: 24700364 Free PMC article.
Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis.
Ariza X, Graupera I, Coll M, Solà E, Barreto R, García E, Moreira R, Elia C, Morales-Ruiz M, Llopis M, Huelin P, Solé C, Fabrellas N, Weiss E, Nevens F, Gerbes A, Trebicka J, Saliba F, Fondevila C, Hernández-Gea V, Fernández J, Bernardi M, Arroyo V, Jiménez W, Deulofeu C, Pavesi M, Angeli P, Jalan R, Moreau R, Sancho-Bru P, Ginès P; CANONIC Investigators, EASL CLIF Consortium. Ariza X, et al. J Hepatol. 2016 Jul;65(1):57-65. doi: 10.1016/j.jhep.2016.03.002. Epub 2016 Mar 14. J Hepatol. 2016. PMID: 26988732 Free article.
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