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Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages.
Taddei RN, Sanchez-Mico MV, Bonnar O, Connors T, Gaona A, Denbow D, Frosch MP, Gómez-Isla T. Taddei RN, et al. Among authors: sanchez mico mv. Acta Neuropathol Commun. 2022 May 9;10(1):72. doi: 10.1186/s40478-022-01370-3. Acta Neuropathol Commun. 2022. PMID: 35534858 Free PMC article.
Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1.
March-Diaz R, Lara-Ureña N, Romero-Molina C, Heras-Garvin A, Ortega-de San Luis C, Alvarez-Vergara MI, Sanchez-Garcia MA, Sanchez-Mejias E, Davila JC, Rosales-Nieves AE, Forja C, Navarro V, Gomez-Arboledas A, Sanchez-Mico MV, Viehweger A, Gerpe A, Hodson EJ, Vizuete M, Bishop T, Serrano-Pozo A, Lopez-Barneo J, Berra E, Gutierrez A, Vitorica J, Pascual A. March-Diaz R, et al. Among authors: sanchez mico mv. Nat Aging. 2021 Apr;1(4):385-399. doi: 10.1038/s43587-021-00054-2. Epub 2021 Apr 15. Nat Aging. 2021. PMID: 37117599
Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease.
Gomez-Arboledas A, Davila JC, Sanchez-Mejias E, Navarro V, Nuñez-Diaz C, Sanchez-Varo R, Sanchez-Mico MV, Trujillo-Estrada L, Fernandez-Valenzuela JJ, Vizuete M, Comella JX, Galea E, Vitorica J, Gutierrez A. Gomez-Arboledas A, et al. Glia. 2018 Mar;66(3):637-653. doi: 10.1002/glia.23270. Epub 2017 Nov 27. Glia. 2018. PMID: 29178139 Free PMC article.
Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis.
Sanchez-Varo R, Sanchez-Mejias E, Fernandez-Valenzuela JJ, De Castro V, Mejias-Ortega M, Gomez-Arboledas A, Jimenez S, Sanchez-Mico MV, Trujillo-Estrada L, Moreno-Gonzalez I, Baglietto-Vargas D, Vizuete M, Davila JC, Vitorica J, Gutierrez A. Sanchez-Varo R, et al. Among authors: sanchez mico mv. Front Neurosci. 2021 Nov 4;15:752594. doi: 10.3389/fnins.2021.752594. eCollection 2021. Front Neurosci. 2021. PMID: 34803589 Free PMC article.
Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer's disease hippocampus.
Muñoz-Castro C, Mejias-Ortega M, Sanchez-Mejias E, Navarro V, Trujillo-Estrada L, Jimenez S, Garcia-Leon JA, Fernandez-Valenzuela JJ, Sanchez-Mico MV, Romero-Molina C, Moreno-Gonzalez I, Baglietto-Vargas D, Vizuete M, Gutierrez A, Vitorica J. Muñoz-Castro C, et al. Among authors: sanchez mico mv. Acta Neuropathol Commun. 2023 Feb 28;11(1):31. doi: 10.1186/s40478-023-01530-z. Acta Neuropathol Commun. 2023. PMID: 36855152 Free PMC article.
Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration.
Sanchez-Mejias E, Navarro V, Jimenez S, Sanchez-Mico M, Sanchez-Varo R, Nuñez-Diaz C, Trujillo-Estrada L, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Sanchez-Mejias E, et al. Acta Neuropathol. 2016 Dec;132(6):897-916. doi: 10.1007/s00401-016-1630-5. Epub 2016 Oct 14. Acta Neuropathol. 2016. PMID: 27743026 Free PMC article.
15 results