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Page 1
Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma.
Ochoa MC, Sanchez-Gregorio S, de Andrea CE, Garasa S, Alvarez M, Olivera I, Glez-Vaz J, Luri-Rey C, Etxeberria I, Cirella A, Azpilikueta A, Berraondo P, Argemi J, Sangro B, Teijeira A, Melero I. Ochoa MC, et al. Among authors: sanchez gregorio s. Cell Rep Med. 2023 Apr 18;4(4):101009. doi: 10.1016/j.xcrm.2023.101009. Epub 2023 Apr 10. Cell Rep Med. 2023. PMID: 37040772 Free PMC article.
Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL-8.
de Andrea CE, Ochoa MC, Villalba-Esparza M, Teijeira Á, Schalper KA, Abengozar-Muela M, Eguren-Santamaría I, Sainz C, Sánchez-Gregorio S, Garasa S, Ariz M, Ortiz-de-Solorzano C, Rodriguez-Ruiz ME, Perez-Gracia JL, Lozano MD, Echeveste JI, Sanmamed MF, Melero I. de Andrea CE, et al. Among authors: sanchez gregorio s. J Pathol. 2021 Oct;255(2):190-201. doi: 10.1002/path.5753. Epub 2021 Aug 5. J Pathol. 2021. PMID: 34184758 Free article.
CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation.
Otano I, Azpilikueta A, Glez-Vaz J, Alvarez M, Medina-Echeverz J, Cortés-Domínguez I, Ortiz-de-Solorzano C, Ellmark P, Fritzell S, Hernandez-Hoyos G, Nelson MH, Ochoa MC, Bolaños E, Cuculescu D, Jaúregui P, Sanchez-Gregorio S, Etxeberria I, Rodriguez-Ruiz ME, Sanmamed MF, Teijeira Á, Berraondo P, Melero I. Otano I, et al. Among authors: sanchez gregorio s. Nat Commun. 2021 Dec 15;12(1):7296. doi: 10.1038/s41467-021-27613-w. Nat Commun. 2021. PMID: 34911975 Free PMC article.
Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity.
Cirella A, Bolaños E, Di Trani CA, de Andrea CE, Sánchez-Gregorio S, Etxeberria I, Gonzalez-Gomariz J, Olivera I, Brocco D, Glez-Vaz J, Luri-Rey C, Azpilikueta A, Rodríguez I, Fernandez-Sendín M, Egea J, Eguren I, Sanmamed MF, Palencia B, Teijeira A, Berraondo P, Melero I. Cirella A, et al. Among authors: sanchez gregorio s. Cancer Immunol Res. 2023 Feb 3;11(2):184-198. doi: 10.1158/2326-6066.CIR-22-0373. Cancer Immunol Res. 2023. PMID: 36478221
Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists.
Cirella A, Bolaños E, Luri-Rey C, Di Trani CA, Olivera I, Gomis G, Glez-Vaz J, Pinci B, Garasa S, Sánchez-Gregorio S, Azpilikueta A, Eguren-Santamaria I, Valencia K, Palencia B, Alvarez M, Ochoa MC, Teijeira Á, Berraondo P, Melero I. Cirella A, et al. Among authors: sanchez gregorio s. Mol Ther Nucleic Acids. 2023 Jul 28;33:668-682. doi: 10.1016/j.omtn.2023.07.026. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37650116 Free PMC article.
Intratumoral co-injection of NK cells and NKG2A-neutralizing monoclonal antibodies.
Melero I, Ochoa MC, Molina C, Sanchez-Gregorio S, Garasa S, Luri-Rey C, Hervas-Stubbs S, Casares N, Elizalde E, Gomis G, Cirella A, Berraondo P, Teijeira A, Alvarez M. Melero I, et al. Among authors: sanchez gregorio s. EMBO Mol Med. 2023 Nov 8;15(11):e17804. doi: 10.15252/emmm.202317804. Epub 2023 Oct 2. EMBO Mol Med. 2023. PMID: 37782273 Free PMC article.
Low-dose ionizing γ-radiation elicits the extrusion of neutrophil extracellular traps.
Teijeira A, Garasa S, Ochoa MC, Sanchez-Gregorio S, Gomis G, Luri-Rey C, Martinez-Monge R, Pinci B, Valencia K, Palencia B, Barbes B, Bolanos E, Azpilikueta A, Garcia-Cardosa M, Burguete J, Eguren-Santamaria I, Garate-Soraluze E, Berraondo P, Perez-Gracia JL, de Andrea CE, Rodriguez-Ruiz ME, Melero I. Teijeira A, et al. Among authors: sanchez gregorio s. Clin Cancer Res. 2024 Apr 17. doi: 10.1158/1078-0432.CCR-23-3860. Online ahead of print. Clin Cancer Res. 2024. PMID: 38630754
CCL20 Expression by Tumor-Associated Macrophages Predicts Progression of Human Primary Cutaneous Melanoma.
Samaniego R, Gutiérrez-González A, Gutiérrez-Seijo A, Sánchez-Gregorio S, García-Giménez J, Mercader E, Márquez-Rodas I, Avilés JA, Relloso M, Sánchez-Mateos P. Samaniego R, et al. Among authors: sanchez gregorio s. Cancer Immunol Res. 2018 Mar;6(3):267-275. doi: 10.1158/2326-6066.CIR-17-0198. Epub 2018 Jan 23. Cancer Immunol Res. 2018. PMID: 29362221