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Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN. Membrez M, et al. Among authors: sanchez garcia jl. Nat Metab. 2024 Mar;6(3):433-447. doi: 10.1038/s42255-024-00997-x. Epub 2024 Mar 19. Nat Metab. 2024. PMID: 38504132 Free PMC article.
Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle.
Rhein P, Desjardins EM, Rong P, Ahwazi D, Bonhoure N, Stolte J, Santos MD, Ovens AJ, Ehrlich AM, Sanchez Garcia JL, Ouyang Q, Yabut JM, Kjolby M, Membrez M, Jessen N, Oakhill JS, Treebak JT, Maire P, Scott JW, Sanders MJ, Descombes P, Chen S, Steinberg GR, Sakamoto K. Rhein P, et al. Among authors: sanchez garcia jl. Mol Metab. 2021 Sep;51:101228. doi: 10.1016/j.molmet.2021.101228. Epub 2021 Mar 30. Mol Metab. 2021. PMID: 33798773 Free PMC article.
Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration.
Sonntag T, Ancel S, Karaz S, Cichosz P, Jacot G, Giner MP, Sanchez-Garcia JL, Pannérec A, Moco S, Sorrentino V, Cantó C, Feige JN. Sonntag T, et al. Among authors: sanchez garcia jl. Front Cell Dev Biol. 2022 Nov 9;10:1049653. doi: 10.3389/fcell.2022.1049653. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36438552 Free PMC article.
Nicotinamide riboside kinase 1 protects against diet and age-induced pancreatic β-cell failure.
Cercillieux A, Ratajczak J, Joffraud M, Sanchez-Garcia JL, Jacot G, Zollinger A, Métairon S, Giroud-Gerbetant J, Rumpler M, Ciarlo E, Valera-Alberni M, Sambeat A, Canto C. Cercillieux A, et al. Among authors: sanchez garcia jl. Mol Metab. 2022 Dec;66:101605. doi: 10.1016/j.molmet.2022.101605. Epub 2022 Sep 20. Mol Metab. 2022. PMID: 36165811 Free PMC article.
Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation.
Valera-Alberni M, Joffraud M, Miro-Blanch J, Capellades J, Junza A, Dayon L, Núñez Galindo A, Sanchez-Garcia JL, Valsesia A, Cercillieux A, Söllner F, Ladurner AG, Yanes O, Cantó C. Valera-Alberni M, et al. Among authors: sanchez garcia jl. Cell Rep. 2021 Aug 24;36(8):109565. doi: 10.1016/j.celrep.2021.109565. Cell Rep. 2021. PMID: 34433037 Free PMC article.
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